{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T00:16:11Z","timestamp":1788480971171,"version":"build-2803163510"},"reference-count":71,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T00:00:00Z","timestamp":1779926400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T00:00:00Z","timestamp":1779926400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100000780","name":"European Commission","doi-asserted-by":"publisher","award":["964553"],"award-info":[{"award-number":["964553"]}],"id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000780","name":"European Commission","doi-asserted-by":"publisher","award":["101099058"],"award-info":[{"award-number":["101099058"]}],"id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002347","name":"Bundesministerium f\u00fcr Bildung und Forschung","doi-asserted-by":"publisher","award":["05K22PSA"],"award-info":[{"award-number":["05K22PSA"]}],"id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002347","name":"Bundesministerium f\u00fcr Bildung und Forschung","doi-asserted-by":"publisher","award":["13GW0622"],"award-info":[{"award-number":["13GW0622"]}],"id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["GRK2887 \u2010 497350882"],"award-info":[{"award-number":["GRK2887 \u2010 497350882"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["SFB 1648\/1 (2024) \u2010 512741711"],"award-info":[{"award-number":["SFB 1648\/1 (2024) \u2010 512741711"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["analyticalsciencejournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Mass Spectrom"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    In conventional native mass spectrometry (MS), one faces severe limitations when challenged with heterogeneous, high\u2010mass samples, commonly failing to resolve clear peak distributions, and thus mass determination. Charge detection MS (CDMS) has emerged as a premier method to analyze these samples by determining mass\u2010to\u2010charge ratio (\n                    <jats:italic>m<\/jats:italic>\n                    \/\n                    <jats:italic>z<\/jats:italic>\n                    ) and charge (\n                    <jats:italic>z<\/jats:italic>\n                    ) simultaneously. Here, the two currently available commercialized CDMS systems, the Orbitrap\u2010based Direct Mass Technology (DMT) and the electrostatic linear ion trap (ELIT)\u2013based Xevo CDMS are applied to human norovirus capsids from two different strains, GI.1 Norwalk and GII.17 Kawasaki. The norovirus capsid is highly heterogeneous due to N\u2010terminal processing on the repeating subunits that it is built from and commonly forms\n                    <jats:italic>T\u2009=<\/jats:italic>\n                    \u20093 and sometimes\n                    <jats:italic>T\u2009=<\/jats:italic>\n                    \u20094 particles. Both CDMS approaches were able to determine similar masses in both strains. GII.17 Kawasaki exhibits both\n                    <jats:italic>T\u2009=<\/jats:italic>\n                    \u20093 and\n                    <jats:italic>T\u2009=<\/jats:italic>\n                    \u20094 particles, though the Xevo CDMS measurements were closer to the theoretical mass than the DMT instrument. Interestingly, GII.17 Kawasaki also displayed nonclassical mass distributions with high abundance in\u2010between\n                    <jats:italic>T\u2009=<\/jats:italic>\n                    \u20093 and\n                    <jats:italic>T\u2009=<\/jats:italic>\n                    \u20094, which was then confirmed by cryogenic electron microscopy (cryo\u2010EM), demonstrating an oval capsid shape. GI.1 Norwalk displays a wide mass distribution in both instruments that exceeds the theoretical\n                    <jats:italic>T\u2009=<\/jats:italic>\n                    \u20093 mass by 8%\u201310%. Proteomics and native MS experiments suggest possible interactions with a protein from the expression system. This study demonstrates the capabilities of two distinct CDMS methodologies on two viral capsids and presents the first nonclassical capsid assembly in a GII.17 noroviral capsid.\n                  <\/jats:p>","DOI":"10.1002\/jms.70068","type":"journal-article","created":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T10:55:47Z","timestamp":1779965747000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Applying Distinct CDMS Strategies to Observe Nonclassical Virus Capsid Assembly"],"prefix":"10.1002","volume":"61","author":[{"given":"Lars","family":"Thiede","sequence":"first","affiliation":[{"name":"CSSB Centre for Structural Systems Biology, Deutsches Elektronen\u2010Synchrotron DESY &amp; Leibniz Institute of Virology (LIV) &amp; University of Luebeck  Hamburg Germany"},{"name":"University of Luebeck, Institute of Chemistry and Metabolomics  L\u00fcbeck Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anisha","family":"Haris","sequence":"additional","affiliation":[{"name":"Waters Corporation  Wilmslow UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomislav","family":"Damjanovi\u0107","sequence":"additional","affiliation":[{"name":"CSSB Centre for Structural Systems Biology, Deutsches Elektronen\u2010Synchrotron DESY &amp; Leibniz Institute of Virology (LIV) &amp; University of Luebeck  Hamburg Germany"},{"name":"University of Luebeck, Institute of Chemistry and Metabolomics  L\u00fcbeck Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jocky C. K.","family":"Kung","sequence":"additional","affiliation":[{"name":"CSSB Centre for Structural Systems Biology, Deutsches Elektronen\u2010Synchrotron DESY &amp; Leibniz Institute of Virology (LIV) &amp; University of Luebeck  Hamburg Germany"},{"name":"University of Luebeck, Institute of Chemistry and Metabolomics  L\u00fcbeck Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00fcrgen","family":"M\u00fcller\u2010Guhl","sequence":"additional","affiliation":[{"name":"CSSB Centre for Structural Systems Biology, Deutsches Elektronen\u2010Synchrotron DESY &amp; Leibniz Institute of Virology (LIV) &amp; University of Luebeck  Hamburg Germany"},{"name":"University of Luebeck, Institute of Chemistry and Metabolomics  L\u00fcbeck Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronja","family":"Pogan","sequence":"additional","affiliation":[{"name":"CSSB Centre for Structural Systems Biology, Deutsches Elektronen\u2010Synchrotron DESY &amp; Leibniz Institute of Virology (LIV) &amp; University of Luebeck  Hamburg Germany"},{"name":"University of Luebeck, Institute of Chemistry and Metabolomics  L\u00fcbeck Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Rothe","sequence":"additional","affiliation":[{"name":"CSSB Centre for Structural Systems Biology, Deutsches Elektronen\u2010Synchrotron DESY &amp; Leibniz Institute of Virology (LIV) &amp; University of Luebeck  Hamburg Germany"},{"name":"University of Luebeck, Institute of Chemistry and Metabolomics  L\u00fcbeck Germany"},{"name":"Molecular Biophysics, Zernike Institute University of Groningen  Groningen the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wiebke","family":"Schultze","sequence":"additional","affiliation":[{"name":"CSSB Centre for Structural Systems Biology, Deutsches Elektronen\u2010Synchrotron DESY &amp; Leibniz Institute of Virology (LIV) &amp; University of Luebeck  Hamburg Germany"},{"name":"University of Luebeck, Institute of Chemistry and Metabolomics  L\u00fcbeck Germany"},{"name":"Bernhard Nocht Institute for Tropical Medicine (BNITM)  Hamburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanne","family":"Ugelstad","sequence":"additional","affiliation":[{"name":"CSSB Centre for Structural Systems Biology, Deutsches Elektronen\u2010Synchrotron DESY &amp; Leibniz Institute of Virology (LIV) &amp; University of Luebeck  Hamburg Germany"},{"name":"University of Luebeck, Institute of Chemistry and Metabolomics  L\u00fcbeck Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Eatough","sequence":"additional","affiliation":[{"name":"Waters Corporation  Wilmslow UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Giles","sequence":"additional","affiliation":[{"name":"Waters Corporation  Wilmslow UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steve","family":"Preece","sequence":"additional","affiliation":[{"name":"Waters Corporation  Wilmslow UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keith","family":"Richardson","sequence":"additional","affiliation":[{"name":"Waters Corporation  Wilmslow UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2751-7750","authenticated-orcid":false,"given":"Jakub","family":"Ujma","sequence":"additional","affiliation":[{"name":"Waters Corporation  Wilmslow UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1991-7922","authenticated-orcid":false,"given":"Charlotte","family":"Uetrecht","sequence":"additional","affiliation":[{"name":"CSSB Centre for Structural Systems Biology, Deutsches Elektronen\u2010Synchrotron DESY &amp; Leibniz Institute of Virology (LIV) &amp; University of Luebeck  Hamburg Germany"},{"name":"University of Luebeck, Institute of Chemistry and Metabolomics  L\u00fcbeck Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,28]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.3c07325"},{"key":"e_1_2_9_3_1","doi-asserted-by":"crossref","unstructured":"K.Schamoni\u2010Kast B.Krichel T.Damjanovi\u0107 T.Kierspel S.Toker andC.Uetrecht \u201cThe Kinetics of SARS\u2010CoV\u20102 nsp7\u201011 Polyprotein Processing and Impact on Complexation With nsp16 \u201d (2024). Preprint at bioRxiv https:\/\/doi.org\/10.1101\/2024.01.06.574466.","DOI":"10.1101\/2024.01.06.574466"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.3389\/frans.2023.1119489"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.1c00696"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.0c04339"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.9b04859"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja061468q"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1021\/jasms.3c00071"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijms.2023.117170"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/mas.21851"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chembiol.2012.04.007"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/jms.5124"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1063\/1.1735813"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/rcm.1290091513"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1063\/1.3628667"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1063\/1.2721408"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac071513s"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1063\/1.1148481"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0168\u2010583X(00)00415\u20108"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.5b02324"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.9b03586"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.1c00377"},{"key":"e_1_2_9_24_1","doi-asserted-by":"crossref","unstructured":"J.Ujma C.Wheeldon A.Schofield et\u00a0al. \u201cThe Design and Characterisation of a New Charge Detection Mass Spectrometry (CDMS) Instrument for the Analysis of Megadalton\u2010Sized Molecules \u201d (2025).","DOI":"10.64898\/2026.05.28.728353"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.4c03267"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13361\u2010019\u201002309\u20100"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jproteome.9b00797"},{"key":"e_1_2_9_28_1","unstructured":"Direct Mass Technology \u2010 DEhttps:\/\/www.thermofisher.com\/de\/de\/home\/industrial\/mass\u2010spectrometry\/liquid\u2010chromatography\u2010mass\u2010spectrometry\u2010lc\u2010ms\/lc\u2010ms\u2010systems\/direct\u2010mass\u2010technology.html."},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41592\u2010024\u201002207\u20108"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2025.1558482"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms10071450"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2024.e34927"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0151219"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/119.6.668"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879\u2010015\u20101168\u20105"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1101\/SQB.1962.027.001.005"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.coviro.2018.05.003"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines9010008"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.66.11.6527\u20106532.1992"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.antiviral.2019.05.010"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.4c01913"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1074\/mcp.M900620\u2010MCP200"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1088\/1361\u2010648X\/aaa43b"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41579\u2010024\u201001144\u20109"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00705\u2010010\u20100768\u2010z"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-031-36815-8_8"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12985\u2010025\u201002796\u20106"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2023.1188431"},{"key":"e_1_2_9_49_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01854\u201006"},{"key":"e_1_2_9_50_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00705\u2010004\u20100406\u20108"},{"key":"e_1_2_9_51_1","doi-asserted-by":"publisher","DOI":"10.1038\/227680a0"},{"key":"e_1_2_9_52_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.1c03181"},{"key":"e_1_2_9_53_1","unstructured":"K.Richardson K.Giles A.Harris B.Draper andM.Jarrold \u201cCalibration of Charge Detection MS Instruments \u201d (2025)."},{"key":"e_1_2_9_54_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1431927603445911"},{"key":"e_1_2_9_55_1","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.4169"},{"key":"e_1_2_9_56_1","doi-asserted-by":"publisher","DOI":"10.3390\/v15071482"},{"key":"e_1_2_9_57_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010022\u201028757\u2010z"},{"key":"e_1_2_9_58_1","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.74.14.6581\u20106591.2000"},{"key":"e_1_2_9_59_1","doi-asserted-by":"publisher","DOI":"10.1006\/viro.2000.0579"},{"key":"e_1_2_9_60_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.03508\u201012"},{"key":"e_1_2_9_61_1","doi-asserted-by":"crossref","unstructured":"J. J.Dave S. E.Crawford R. L.Atmar K.Ettayebi B. V. V.Prasad andM. K.Estes \u201cMutational Analysis of Human Norovirus VP2 Elucidates Critical Molecular Interactions for Virus Assembly \u201d (2025) bioRxiv 2025.08.23.671901 https:\/\/doi.org\/10.1101\/2025.08.23.671901.","DOI":"10.1101\/2025.08.23.671901"},{"key":"e_1_2_9_62_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586\u2010018\u20100852\u20101"},{"key":"e_1_2_9_63_1","unstructured":"UniProt UniProt https:\/\/www.uniprot.org\/uniprotkb\/Q83885\/entry."},{"key":"e_1_2_9_64_1","doi-asserted-by":"publisher","DOI":"10.1016\/0042\u20106822(85)90107\u20102"},{"key":"e_1_2_9_65_1","doi-asserted-by":"publisher","DOI":"10.1006\/viro.1995.1291"},{"key":"e_1_2_9_66_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac050511"},{"key":"e_1_2_9_67_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.accounts.3c00079"},{"key":"e_1_2_9_68_1","doi-asserted-by":"crossref","unstructured":"A. F. R.Gr\u00fcn F.\u2010A.Said K.Schamoni\u2010Kast T.Damjanovic J.Bosse andC.Uetrecht \u201cFast Tracking Native Mass Spectrometry: Skipping Over Buffer Exchange \u201d (2025). Preprint at bioRxiv https:\/\/doi.org\/10.1101\/2025.02.22.639503.","DOI":"10.1101\/2025.02.22.639503"},{"key":"e_1_2_9_69_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.1c00212"},{"key":"e_1_2_9_70_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0039793"},{"key":"e_1_2_9_71_1","doi-asserted-by":"publisher","DOI":"10.1039\/D3CP06344E"},{"key":"e_1_2_9_72_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.286.5438.287"}],"container-title":["Journal of Mass Spectrometry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jms.70068","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jms.70068","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jms.70068","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T22:14:24Z","timestamp":1781820864000},"score":1,"resource":{"primary":{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/10.1002\/jms.70068"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,28]]},"references-count":71,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["10.1002\/jms.70068"],"URL":"https:\/\/doi.org\/10.1002\/jms.70068","archive":["Portico"],"relation":{},"ISSN":["1076-5174","1096-9888"],"issn-type":[{"value":"1076-5174","type":"print"},{"value":"1096-9888","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,28]]},"assertion":[{"value":"2026-01-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-07","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-28","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70068"}}