{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T13:54:50Z","timestamp":1761486890837},"reference-count":12,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2002,11,14]],"date-time":"2002-11-14T00:00:00Z","timestamp":1037232000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2003,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This study was undertaken to investigate the value of HPV testing in women referred with two abnormal smears that were graded as mild dyskaryosis or less who attended for at least three follow\u2010up visits. One hundred forty\u2010nine women were included in the study and a total of 39 high\u2010grade lesions including one cancer were detected. All of these were found to be associated with the persistent presence of one or more of 13 high\u2010risk human papillomavirus types (HPV) as detected by a multiplex type specific PCR technique. Two high\u2010grade lesions were initially missed by cytology. In contrast, no cytological or histological evidence of high\u2010grade lesions was found during a follow\u2010up period of up to 8 years in 62 women with no high\u2010risk HPV infection or in 38 women with only transient high\u2010risk HPV infection. The utility of high\u2010risk HPV detection in the management of women presenting with mild cytological abnormalities is discussed. J. Med. Virol. 69:118\u2013121, 2003. \u00a9 2003 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/jmv.10257","type":"journal-article","created":{"date-parts":[[2002,11,18]],"date-time":"2002-11-18T13:44:13Z","timestamp":1037627053000},"page":"118-121","source":"Crossref","is-referenced-by-count":10,"title":["Human papillomavirus DNA detection in the management of women with twice mildly abnormal cytological smears"],"prefix":"10.1002","volume":"69","author":[{"given":"Linda","family":"Ho","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George","family":"Terry","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip","family":"Londesborough","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jack","family":"Cuzick","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felipe","family":"Lorenzato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Albert","family":"Singer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2002,11,15]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/90.1.50"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1999.tb08439.x"},{"key":"e_1_2_1_4_1","first-page":"125","article-title":"Triage of women with ASCUS and LSIL on Pap smear reports: management by repeat Pap smear, HPV DNA testing or colposcopy?","volume":"46","author":"Ferris DG","year":"1998","journal-title":"J Fam Pract"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/92.6.464"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0215(19961021)69:5<364::AID-IJC2>3.0.CO;2-3"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006250-199203000-00002"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1994.tb11952.x"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/90.1.43"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(98)12490-X"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.2015"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)02402-8"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/path.981"}],"container-title":["Journal of Medical Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjmv.10257","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmv.10257","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,14]],"date-time":"2023-10-14T01:37:28Z","timestamp":1697247448000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmv.10257"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,11,15]]},"references-count":12,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2003,1]]}},"alternative-id":["10.1002\/jmv.10257"],"URL":"https:\/\/doi.org\/10.1002\/jmv.10257","archive":["Portico"],"relation":{},"ISSN":["0146-6615","1096-9071"],"issn-type":[{"value":"0146-6615","type":"print"},{"value":"1096-9071","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,11,15]]}}}