{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T06:06:48Z","timestamp":1773986808130,"version":"3.50.1"},"reference-count":20,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2003,5,6]],"date-time":"2003-05-06T00:00:00Z","timestamp":1052179200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"FONDECYT","award":["1981071"],"award-info":[{"award-number":["1981071"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2003,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Infantile chronic recurrent parotitis (ICRP) has been attributed to multiple causes, including viral infections, and therefore its treatment remains empirical. Our aim was to evaluate the involvement of respiratory and oropharyngeal viruses in acute episodes of ICRP. Seventy children were studied, 50 patients and 20 age\u2010matched controls, in a 2\u2010year follow\u2010up study. Saliva samples were taken from the parotid duct and analyzed by viral isolation and immunofluorescence for adenovirus (Ad), respiratory sincitial virus (RSV), parainfluenza virus (PI), influenza virus (Flu), Cytomegalovirus (CMV), and herpes simplex virus (HSV). Paired sera samples were tested by ELISA for anti\u2010Epstein\u2010Barr virus (EBV) IgG and anti\u2010mumps IgM and IgG. Viral infections were detected in 7\/50 (14%) cases of the ICRP group: one CMV; 2 Enteroviruses isolated in human embryonic lung fibroblast cells; 1 Flu A; and 3 mumps virus. No EBV seroconversions were detected. In the control group, 2 out of the 20 children had an asymptomatic mumps positive IgM titer. Our data indicate that the main respiratory and oropharyngeal viruses are not the cause of acute episodes of ICRP in Chilean children. J. Med. Virol. 70:459\u2013462, 2003. \u00a9 2003 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/jmv.10417","type":"journal-article","created":{"date-parts":[[2003,5,21]],"date-time":"2003-05-21T10:02:00Z","timestamp":1053511320000},"page":"459-462","source":"Crossref","is-referenced-by-count":18,"title":["Virology of infantile chronic recurrent parotitis in Santiago de Chile"],"prefix":"10.1002","volume":"70","author":[{"given":"Claudia","family":"Vinagre","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda Jos\u00e9","family":"Mart\u00ednez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis Fidel","family":"Avenda\u00f1o","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mirta","family":"Landaeta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda Eugenia","family":"Pinto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2003,5,6]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(83)91038-3"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006454-199108000-00003"},{"key":"e_1_2_1_4_1","volume-title":"Laboratory methods for diagnosing respiratory virus infections","author":"Ballew H","year":"1984"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-196605000-00009"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348949110000702"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.1983.tb09709.x"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(85)90361-5"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(86)90091-5"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348948809700403"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006454-199704000-00010"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.28.139.182"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(78)90039-9"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/00034894790886S301"},{"key":"e_1_2_1_15_1","first-page":"67","article-title":"Diagn\u00f3stico de infecci\u00f3n por Adenovirus y Virus Sincicial respiratorio en lactantes","volume":"7","author":"Larra\u00f1aga C","year":"1990","journal-title":"Rev Chile Infectol"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9071(200003)60:3<342::AID-JMV14>3.0.CO;2-0"},{"key":"e_1_2_1_17_1","first-page":"22","article-title":"Recurrent parotitis in children","volume":"61","author":"Mandel L","year":"1995","journal-title":"NY State Dent J"},{"key":"e_1_2_1_18_1","first-page":"55","article-title":"Detecci\u00f3n de excreci\u00f3n oral de virus herpes simplex en pacientes con queratitis herp\u00e9tica mediante cultivo convencional y PCR","volume":"2","author":"Mart\u00ednez MJ","year":"1998","journal-title":"Rev Panam Infectol"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(79)92384-5"},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.4850.1359"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800730922"}],"container-title":["Journal of Medical Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjmv.10417","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmv.10417","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,17]],"date-time":"2023-11-17T14:17:12Z","timestamp":1700230632000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmv.10417"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,5,6]]},"references-count":20,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2003,7]]}},"alternative-id":["10.1002\/jmv.10417"],"URL":"https:\/\/doi.org\/10.1002\/jmv.10417","archive":["Portico"],"relation":{},"ISSN":["0146-6615","1096-9071"],"issn-type":[{"value":"0146-6615","type":"print"},{"value":"1096-9071","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,5,6]]}}}