{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T23:59:38Z","timestamp":1778543978597,"version":"3.51.4"},"reference-count":32,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2003,7,8]],"date-time":"2003-07-08T00:00:00Z","timestamp":1057622400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2003,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Seoul (SEO) viruses belong to the <jats:italic>Hantavirus<\/jats:italic> genus (family Bunyaviridae), cause the moderate form of haemorrhagic fever with renal syndrome, and have been associated with laboratory\u2010acquired infections in many countries. To investigate the pedigree of an isolate, designated IR461, which was obtained from a laboratory\u2010acquired infection in a UK research institute, we determined the nucleotide sequences of the small (S) and medium (M) genome segments. In addition, we determined the sequences of the S segments of two Chinese isolates (R22 and L99) and an American isolate (Tchoupitoulas [TCH]). The S segments range within 1769\u20131785 nucleotides in length and showed identities of &gt;88% in nucleotide sequence and 97% in amino acid sequence to those of published S segment sequences. The M RNA segment of IR461 is 3651 nucleotides long and shows &gt;84% identity at the nucleotide level and &gt;98% at the amino acid level to the M segments of other SEO viruses. These data confirm that SEO viruses show the least diversity within the <jats:italic>Hantavirus<\/jats:italic> genus. Phylogenetic analyses of the sequences showed geographic clustering of the Chinese SEO viruses, and that IR461 was more closely related to SEO viruses isolated in the New World than to those from the Far East. J. Med. Virol. 71:105\u2013109, 2003. \u00a9 2003 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/jmv.10446","type":"journal-article","created":{"date-parts":[[2003,7,9]],"date-time":"2003-07-09T10:06:37Z","timestamp":1057745197000},"page":"105-109","source":"Crossref","is-referenced-by-count":20,"title":["Genetic characterisation of a hantavirus isolated from a laboratory\u2010acquired infection"],"prefix":"10.1002","volume":"71","author":[{"given":"Xiaohong","family":"Shi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Conall","family":"McCaughey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard M.","family":"Elliott","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2003,7,8]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0168-1702(92)90029-9"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0042-6822(90)90236-K"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a114662"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(83)90797-3"},{"key":"e_1_2_1_6_1","first-page":"599","volume-title":"Virus taxonomy. 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