{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T18:25:05Z","timestamp":1791397505264,"version":"4.3.3"},"reference-count":40,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2003,8,18]],"date-time":"2003-08-18T00:00:00Z","timestamp":1061164800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2003,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A 55\u2010year\u2010old bat conservationist was admitted to Ninewells Hospital, Dundee, Scotland, on November 11, 2002, with an acute haematemesis. He gave a 5\u2010day history of pain and paraesthesia in the left arm, followed by increasing weakness of his limbs with evidence of an evolving encephalitis with cerebellar involvement. The patient had never been vaccinated against rabies and did not receive postexposure treatment. Using a hemi\u2010nested reverse transcriptase\u2010polymerase chain reaction (RT\u2010PCR), saliva samples taken intravitam from different dates proved positive for rabies. A 400\u2010bp region of the nucleoprotein gene was sequenced for confirmation and identified a strain of European bat lyssavirus (EBLV) type 2a. The diagnosis was confirmed using the fluorescent antibody test (FAT) and by RT\u2010PCR on three brain samples (cerebellum, medulla, and hippocampus) taken at autopsy. In addition, a mouse inoculation test (MIT) was performed. Between 13 and 17 days postinfection, clinical signs of a rabies\u2010like illness had developed in all five inoculated mice. Brain smears from each infected animal were positive by the FAT and viable virus was isolated. This fatal incident is only the second confirmed case of an EBLV type\u20102 infection in a human after exposure to bats. J. Med. Virol. 71:281\u2013289, 2003. Copyright \u00a9 Crown Copyright 2003. Recorded with the permission of the controller of the Majesty's Stationery Office. Published by Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/jmv.10481","type":"journal-article","created":{"date-parts":[[2003,8,22]],"date-time":"2003-08-22T14:29:20Z","timestamp":1061562560000},"page":"281-289","source":"Crossref","is-referenced-by-count":140,"title":["Case report: Isolation of a European bat lyssavirus type 2a from a fatal human case of rabies encephalitis"],"prefix":"10.1002","volume":"71","author":[{"given":"Anthony R.","family":"Fooks","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorraine M.","family":"McElhinney","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Derrick J.","family":"Pounder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher J.","family":"Finnegan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen","family":"Mansfield","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharon M.","family":"Brookes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Graham","family":"Parsons","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathleen","family":"White","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul G.","family":"McIntyre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dilip","family":"Nathwani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2003,8,18]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-78-9-2319"},{"key":"e_1_2_1_3_1","first-page":"12","article-title":"Bat rabies in the Union of Soviet Socialist Republics","volume":"10","author":"Anonymous","year":"1986","journal-title":"Rabies Bull Eur"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.30.9.2419-2426.1992"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-1759(97)00212-3"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.2307\/4591470"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid0901.020104"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.36.4.1117-1121.1998"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid0902.020218"},{"key":"e_1_2_1_10_1","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1017\/S0317167100026329","article-title":"Massive necrosis of the brain in rabies","volume":"14","author":"Dolman CL","year":"1987","journal-title":"Can J Neurobiol Sci"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1981.30.1113"},{"key":"e_1_2_1_12_1","unstructured":"FooksAR JohnsonN BrookesS McElhinneyLM.2002.Genetic diversity of emerging zoonotic lyssaviruses. 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