{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T20:45:23Z","timestamp":1789073123568,"version":"build-2803163510"},"reference-count":32,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2005,12,9]],"date-time":"2005-12-09T00:00:00Z","timestamp":1134086400000},"content-version":"vor","delay-in-days":10569,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[1977,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Closely related human and monkey orthopoxviruses were differentiated by serologic techniques. Antiviral sera were tested by immunodiffusion for reactivity against six different viral antigens prepared from either infected cell cultures or infected chorioallantoic membranes (CAMs) of embryonated eggs. Portions of each antiserum were separately absorbed with heterologous antigens from infected CAMs to remove common reactivity. The absorbed sera formed immunodiffusion precipitates with both types of antigen preparation and revealed specific\u2010character differences that made it possible to classify the viruses as variola, vaccinia, or monkeypox. Cross\u2010complement fixation tests were also used to examine the immunologic reactivities of antisera to detergent\u2010treated, purified preparations of three orthopoxviruses. Only common reactivities were detected by this method, however, and differentiating reactivities were not observed.<\/jats:p>","DOI":"10.1002\/jmv.1890010107","type":"journal-article","created":{"date-parts":[[2007,3,2]],"date-time":"2007-03-02T07:17:46Z","timestamp":1172819866000},"page":"35-47","source":"Crossref","is-referenced-by-count":29,"title":["Serological relatedness of monkeypox, variola, and vaccinia viruses"],"prefix":"10.1002","volume":"1","author":[{"given":"Joseph J.","family":"Esposito","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John F.","family":"Obijeski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James H.","family":"Nakano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,12,9]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"373","volume-title":"Viruses of Vertebrates","author":"Andrewes CH","year":"1972"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0042-6822(65)90030-9"},{"key":"e_1_2_1_4_1","first-page":"215","article-title":"Identification and interrelationships of the variola\/vaccinia subgroup of poxviruses","volume":"19","author":"Baxby D","year":"1975","journal-title":"Progress in Medical Virology"},{"key":"e_1_2_1_5_1","first-page":"487","volume-title":"Infectious Agents and Host Reactions","author":"Downie AW","year":"1970"},{"key":"e_1_2_1_6_1","first-page":"158","article-title":"The immunological relationship of the virus of spontaneous cowpox to vaccinia virus","volume":"20","author":"Downie AW","year":"1939","journal-title":"British Journal of Experimental Pathology"},{"key":"e_1_2_1_7_1","first-page":"281","volume-title":"Diagnostic Procedures for Viral and Rickettsial Infections","author":"Downie AW","year":"1969"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/path.1700910220"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/129.3.289"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0042-6822(67)90072-4"},{"key":"e_1_2_1_11_1","first-page":"633","article-title":"Human infection with monkeypox virus: Laboratory investigation of six cases in West Africa","volume":"46","author":"Lourie B","year":"1972","journal-title":"Bulletin of the World Health Organization"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1699-0463.1959.tb00328.x"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.174.4015.1247"},{"key":"e_1_2_1_14_1","first-page":"613","article-title":"Poxviruses isolated from clinically ill and asymptomatically infected monkeys and a chimpanzee","volume":"46","author":"Marennikova SS","year":"1972","journal-title":"Bulletin of the World Health Organization"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01245774"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01257729"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0450.1972.tb00371.x"},{"key":"e_1_2_1_18_1","volume-title":"Comparative Diagnosis of Viral Diseases","author":"Nakano JH","year":"1976"},{"key":"e_1_2_1_19_1","first-page":"782","volume-title":"Manual of Clinical Microbiology","author":"Nakano JH","year":"1974"},{"key":"e_1_2_1_20_1","first-page":"374","article-title":"Antigenes solubles des \u201cpox virus.\u201d I. 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Public Health Service Center for Disease Control pp1\u201356."},{"issue":"3","key":"e_1_2_1_25_1","first-page":"65","article-title":"Eine \u201cmonkey\u2010Pox\u201d Enzootie im Affenhaus des Tiergartens \u201cBlijdorp.\u201d","volume":"11","author":"Peters JC","year":"1966","journal-title":"Die Kleintier\u2010Praxis"},{"key":"e_1_2_1_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1960.tb50015.x"},{"key":"e_1_2_1_27_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022172400039292"},{"key":"e_1_2_1_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01241954"},{"key":"e_1_2_1_29_1","doi-asserted-by":"crossref","first-page":"4505","DOI":"10.1016\/S0021-9258(18)62040-X","article-title":"Reversible denaturation of enzymes by sodium dodecyl sulfate","volume":"246","author":"Weber K","year":"1971","journal-title":"Journal of Biological Chemistry"},{"key":"e_1_2_1_30_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/978-3-642-46160-6_1","article-title":"The poxvirus antigens","volume":"47","author":"Wilcox WC","year":"1969","journal-title":"Current Topics in Microbiology and Immunology."},{"key":"e_1_2_1_31_1","first-page":"1","volume-title":"Guide to the Laboratory Diagnosis of Smallpox for Smallpox Eradication Programmes","year":"1969"},{"key":"e_1_2_1_32_1","first-page":"567","article-title":"\u201cMonkeypox\u201d (a series of nine articles","volume":"46","author":"World Health Organization.","year":"1972","journal-title":"Bulletin of the World Health Organization"},{"key":"e_1_2_1_33_1","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1093\/oxfordjournals.aje.a121075","article-title":"Serologic response of children after primary vaccination and revaccination against smallpox","volume":"99","author":"Wulff H","year":"1969","journal-title":"American Journal of Epidemiology"}],"container-title":["Journal of Medical Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjmv.1890010107","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmv.1890010107","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,12]],"date-time":"2023-11-12T23:57:01Z","timestamp":1699833421000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmv.1890010107"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1977,1]]},"references-count":32,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1977,1]]}},"alternative-id":["10.1002\/jmv.1890010107"],"URL":"https:\/\/doi.org\/10.1002\/jmv.1890010107","archive":["Portico"],"relation":{},"ISSN":["0146-6615","1096-9071"],"issn-type":[{"value":"0146-6615","type":"print"},{"value":"1096-9071","type":"electronic"}],"subject":[],"published":{"date-parts":[[1977,1]]}}}