{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T22:21:00Z","timestamp":1767651660535},"reference-count":28,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2005,12,7]],"date-time":"2005-12-07T00:00:00Z","timestamp":1133913600000},"content-version":"vor","delay-in-days":10202,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[1978,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Newborn hamsters were inoculated intracerebrally with measles virus materials from Lu 106 and Vero carrier cell lines. Extracellular and cell\u2010associated materials from cultures incubated at 37\u00b0C and at 33\u00b0C were used. The lower temperature allows accentuated virus replication. No animals contracted acute encephalitis, but 8 animals developed advanced neurological disease (unsteady gait, serial myoclonic jerks, hypoactivity) 79 to 212 days after injection. Seven out of these 8 animals belonged to a group of 50 animals, which had been inoculated with cell\u2010associated material from cultures incubated at 33\u00b0C. Viral antigen and nucleocapsids were found in neurons and glial cells from diseased animals, which showed degenerative changes and inflammation, particularly in the mesencephalon. Some of these animals also had hydrocephalus, which, however, also occurred in many apparently healthy animals. Also this pathological alteration occurred most frequently (5 out of 11 animals examined 9\u201310 months after inoculation) in hamsters receiving cell\u2010associated material from carrier cultures incubated at 33\u00b0C. Possible mechanisms for the appearance of hydrocephalus are discussed.<\/jats:p>","DOI":"10.1002\/jmv.1890020404","type":"journal-article","created":{"date-parts":[[2007,3,2]],"date-time":"2007-03-02T08:14:59Z","timestamp":1172823299000},"page":"305-317","source":"Crossref","is-referenced-by-count":12,"title":["Subacute encephalitis and hydrocephalus in hamsters caused by measles virus from persistently infected cell cultures"],"prefix":"10.1002","volume":"2","author":[{"given":"Erling","family":"Norrby","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kirster","family":"Kristensson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,12,7]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.831255"},{"key":"e_1_2_1_3_1","first-page":"335","article-title":"Experimental measles virus encephalitis. 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