{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:38:46Z","timestamp":1760146726824},"reference-count":12,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2005,12,6]],"date-time":"2005-12-06T00:00:00Z","timestamp":1133827200000},"content-version":"vor","delay-in-days":9836,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[1979,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The results of a pilot study on the prevalence of anti\u2010HBc in HBsAg negative volunteer blood donors are presented.<\/jats:p><jats:p>Two techniques for anti\u2010HBc determination were compared \u2014 radio\u2014immunoassay (RIA) and indirect immunofluorescence (IF). In a panel of 56 sera with known HBV markers, RIA was found to be significantly more sensitive than IF, and both techniques were specific. Out of 2,000 HBsAg negative blood donor sera tested by RIA,46 (2.3%) were found positive for anti\u2010HBc. In 24\/24 sera, the specificity of the anti\u2010HBc was confirmed. Also 37\/46 (80.4%) anti\u2010HBc positives were found positive for anti\u2010HBs, leaving 9\/2, OOC (0.4%) blood donors positive only for anti\u2010HBc.<\/jats:p><jats:p>It is concluded that it would be premature to advocate the introduction of anti\u2010HBc as a routine screening test of blood donors.<\/jats:p>","DOI":"10.1002\/jmv.1890030405","type":"journal-article","created":{"date-parts":[[2007,3,2]],"date-time":"2007-03-02T08:50:32Z","timestamp":1172825432000},"page":"275-280","source":"Crossref","is-referenced-by-count":5,"title":["Hepatitis B core antibody in volunteer blood donors: Comparison of radioimmunoassay and indirect immunofluorescence"],"prefix":"10.1002","volume":"3","author":[{"given":"J. N.","family":"Katchaki","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T. H.","family":"Siem","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Brouwer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,12,6]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(71)90543-5"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/127.4.424"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.30.8.709"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000441-197509000-00015"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(73)92004-7"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197406132902402"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197308232890801"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.31.9.837"},{"key":"e_1_2_1_10_1","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1093\/ajcp\/66.4.731","article-title":"Significance of anti\u2010HBc in patients with hepatic disease. A comparative immunohistochemical study of blood and hepatic tissue","volume":"66","author":"Kater L","year":"1976","journal-title":"Am J Clin Pathol"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1423-0410.1978.tb03726.x"},{"key":"e_1_2_1_12_1","first-page":"83","article-title":"Radioimmune assay for anti\u2010core as evidence for exposure to hepatitis B virus. Rush\u2010Presbyt.\u2010St","volume":"15","author":"Overby LR","year":"1976","journal-title":"Luke's Med Bull"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1159\/000149428"}],"container-title":["Journal of Medical Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjmv.1890030405","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmv.1890030405","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,12]],"date-time":"2023-11-12T23:16:01Z","timestamp":1699830961000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmv.1890030405"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1979,1]]},"references-count":12,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1979,1]]}},"alternative-id":["10.1002\/jmv.1890030405"],"URL":"https:\/\/doi.org\/10.1002\/jmv.1890030405","archive":["Portico"],"relation":{},"ISSN":["0146-6615","1096-9071"],"issn-type":[{"value":"0146-6615","type":"print"},{"value":"1096-9071","type":"electronic"}],"subject":[],"published":{"date-parts":[[1979,1]]}}}