{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T01:12:50Z","timestamp":1778634770331,"version":"3.51.4"},"reference-count":4,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2005,12,6]],"date-time":"2005-12-06T00:00:00Z","timestamp":1133827200000},"content-version":"vor","delay-in-days":9105,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[1981,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In a study in Kenya of corneal lesions occurring in children with measles virus infection, conjunctival lesions of a characteristic appearance were seen concomitant with the rash. The lesions became visible after staining by Lissamine green or Rose Bengal.<\/jats:p><jats:p>In order to investigate whether these lesions were virus\u2010induced, paired biopsies were performed on the conjunctiva of five measles patients. One biopsy was taken of a staining lesion; the other one, taken of nonstaining conjunctiva of the same eye, served as control.<\/jats:p><jats:p>Measles\u2010specific immunofluorescence on cryostate sections of the biopsies showed that in all patients the antigen occurred in the conjunctival epithelial cell layer in the staining lesions only.<\/jats:p><jats:p>The coincidence of epithelial staining and presence of measles antigen suggests a viral origin of the conjunctival lesion. Fluorescent antibody technique on cryostate sections proved to be a suitable method to demonstrate the presence of virus where isolation fails and serology is not applicable.<\/jats:p>","DOI":"10.1002\/jmv.1890070210","type":"journal-article","created":{"date-parts":[[2007,3,2]],"date-time":"2007-03-02T10:43:33Z","timestamp":1172832213000},"page":"157-162","source":"Crossref","is-referenced-by-count":13,"title":["Detection of measles antigen in conjunctival epithelial lesions staining by lissamine green during measles virus infection"],"prefix":"10.1002","volume":"7","author":[{"given":"F. E.","family":"Nommensen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N. W. H. M.","family":"Dekkers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,12,6]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"crossref","unstructured":"DekkersNWHM: (1981):The cornea in measles. Documenta Opthalmologica: in press.","DOI":"10.1007\/978-94-009-8677-0"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(75)80698-6"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/134.5.463"},{"key":"e_1_2_1_5_1","first-page":"341","article-title":"Studies with measles virus. II. Isolation of virus and immunologic studies in persons who have had the natural disease","volume":"78","author":"Ruckle G","year":"1957","journal-title":"Journal of Immunology"}],"container-title":["Journal of Medical Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjmv.1890070210","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmv.1890070210","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,13]],"date-time":"2023-11-13T04:15:53Z","timestamp":1699848953000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmv.1890070210"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1981,1]]},"references-count":4,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1981,1]]}},"alternative-id":["10.1002\/jmv.1890070210"],"URL":"https:\/\/doi.org\/10.1002\/jmv.1890070210","archive":["Portico"],"relation":{},"ISSN":["0146-6615","1096-9071"],"issn-type":[{"value":"0146-6615","type":"print"},{"value":"1096-9071","type":"electronic"}],"subject":[],"published":{"date-parts":[[1981,1]]}}}