{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T16:31:20Z","timestamp":1759336280958},"reference-count":20,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2005,12,6]],"date-time":"2005-12-06T00:00:00Z","timestamp":1133827200000},"content-version":"vor","delay-in-days":8740,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[1982,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A hemadsorption immunosorbent technique (HIT) was developed for the detection of immunoglobulin M (IgM) to parainfluenza virus types 1, 2, and 3. Twenty\u2010six (90%) of twenty\u2010nine patients under 6 yr of age from whom parainfluenza virus was isolated showed parainfluenza IgM antibody in one or both of their paired sera, with titres ranging from 320 to 81,920. In about one third of the cases IgM antibody was demonstrated in the initial sera taken 1 to 3 days after the onset of illness. Heterotypic IgM antibody responses were observed in about 20% of the patients. The HIT test was more sensitive than the hemagglutination inhibition (HI) and complement fixation tests in detecting a seroresponse in the 29 viruspositive children. The results of studies in older patients with HI titre rises to parainfluenza virus suggested that reinfection probably induced IgM antibody in a proportion of cases. The HIT test proved to be specific for the IgM class of antibody and avoided false\u2010positive results due to rheumatoid factor. It permits an early presumptive diagnosis in a proportion of patients with parainfluenza infection.<\/jats:p>","DOI":"10.1002\/jmv.1890100307","type":"journal-article","created":{"date-parts":[[2007,3,2]],"date-time":"2007-03-02T11:06:14Z","timestamp":1172833574000},"page":"213-221","source":"Crossref","is-referenced-by-count":13,"title":["Detection of parainfluenza IgM antibody by hemadsorption immunosorbent technique"],"prefix":"10.1002","volume":"10","author":[{"given":"J. T. M. Der","family":"Van Logt","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. M.","family":"van Loon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. Van Der","family":"Veen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,12,6]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02125499"},{"key":"e_1_2_1_3_1","unstructured":"CaseyHL(1965):Adaptation of LBCF\u2010method Microtechnique. In \u201cStandardized Diagnostic Complement Fixation and Adaptation to Microtest.\u201d US Public Health Monograph 74. Washington DC: US Government Printing Office pp.1\u201334."},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.104.4.555"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.50.12.1858"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a112125"},{"key":"e_1_2_1_7_1","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1128\/jcm.13.4.698-704.1981","article-title":"Diagnosis of recent rubella virus infection by demonstration of specific immunoglobulin M antibodies: Comparison of solid\u2010phase reverse immunosorbent test with sucrose density gradient centrifugation","volume":"13","author":"Denoyel GA","year":"1981","journal-title":"Journal of Clinical Microbiology"},{"key":"e_1_2_1_8_1","first-page":"585","volume-title":"Diagnostic procedures for Viral, Rickettsial, and Chlamydial infections","author":"Dowdle WA","year":"1979"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.49.1.8"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0166-0934(81)90057-4"},{"key":"e_1_2_1_11_1","first-page":"534","article-title":"Studies of parainfluenza viruses II. Serologic interrelationships in humans","volume":"35","author":"Hsiung GD","year":"1963","journal-title":"The Yale Journal of Biology and Medicine"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.32.1.90"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-44-2-281"},{"key":"e_1_2_1_14_1","first-page":"783","article-title":"Serologic responses to parainfluenza viruses in patients with mumps virus infection","volume":"61","author":"Lennette EH","year":"1963","journal-title":"Journal of Laboratory and Clinical Medicine"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a121514"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.52.6.907"},{"key":"e_1_2_1_17_1","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1128\/jcm.11.4.319-323.1980","article-title":"Enzyme\u2010linked immunosorbent assay for mumps and parainfluenza type 1 immunoglobulin G and immunoglobulin M antibodies","volume":"11","author":"Ukkonen P","year":"1980","journal-title":"Journal of Clinical Microbiology"},{"key":"e_1_2_1_18_1","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1128\/jcm.13.3.410-415.1981","article-title":"Hemadsorption immunosorbent technique for determination of rubella immunoglobulin M antibody","volume":"13","author":"van der Logt JTM","year":"1981","journal-title":"Journal of Clinical Microbiology"},{"key":"e_1_2_1_19_1","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1128\/jcm.15.1.82-86.1982","article-title":"Hemadsorption Immunosorbent technique for determination of mumps immunoglobulin M antibody","volume":"15","author":"van der Logt JTM","year":"1982","journal-title":"Journal of Clinical Microbiology"},{"key":"e_1_2_1_20_1","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1128\/jcm.13.3.416-422.1981","article-title":"Direct enzyme\u2010linked immunosorbent assay that uses peroxidase\u2010labeled antigen for determination of immunoglobulin M antibody to cytomegalovirus","volume":"13","author":"van Loon AM","year":"1981","journal-title":"Journal of Clinical Microbiology"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01245218"}],"container-title":["Journal of Medical Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjmv.1890100307","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmv.1890100307","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,13]],"date-time":"2023-11-13T00:46:27Z","timestamp":1699836387000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmv.1890100307"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1982,1]]},"references-count":20,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1982,1]]}},"alternative-id":["10.1002\/jmv.1890100307"],"URL":"https:\/\/doi.org\/10.1002\/jmv.1890100307","archive":["Portico"],"relation":{},"ISSN":["0146-6615","1096-9071"],"issn-type":[{"value":"0146-6615","type":"print"},{"value":"1096-9071","type":"electronic"}],"subject":[],"published":{"date-parts":[[1982,1]]}}}