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Totally 74% of all HBsAg\u2010positive children had an HBsAg\u2010positive mother or father and an additional 7% had a positive sibling. The distribution of these cases indicated that the risk of HBs\u2010antigenemia was increased 11\u2010fold for those who had an HBsAg\u2010positive mother compared with all other children.<\/jats:p><jats:p>The presence of HBeAg in the HBsAg\u2010positive parents was associated with a threefold higher risk of HBs\u2010antigenemia in children as compared with the presence of anti\u2010HBe.<\/jats:p><jats:p>It was thus documented that HBV in this population is spread primarily by intrafamilial routes and prophylactic measures within risk families should largely be able to control the appearance of new HBsAg carriers.<\/jats:p>","DOI":"10.1002\/jmv.1890110206","type":"journal-article","created":{"date-parts":[[2007,3,2]],"date-time":"2007-03-02T11:18:31Z","timestamp":1172834311000},"page":"125-129","source":"Crossref","is-referenced-by-count":12,"title":["Hepatitis B infection in vietnamese families"],"prefix":"10.1002","volume":"11","author":[{"given":"P.","family":"Skinh\u00f8j","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Kjersem","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Aldershvile","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Black","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,12,8]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/142.1.18"},{"key":"e_1_2_1_3_1","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1093\/oxfordjournals.aje.a112362","article-title":"Epidemiology of hepatitis B in two Alaskan communities","volume":"105","author":"Barrett DH","year":"1977","journal-title":"American Journal of Epidemiology"},{"key":"e_1_2_1_4_1","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1093\/oxfordjournals.aje.a112370","article-title":"The e antigen and vertical transmission of hepatitis B surface antigen","volume":"105","author":"Beasley R","year":"1981","journal-title":"American Journal of Epidemiology"},{"key":"e_1_2_1_5_1","first-page":"1129","article-title":"Hepatocellular carcinoma and hepatitis B virus","volume":"2","author":"Beasley R","year":"1977","journal-title":"Lancet"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.6118.949"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(76)91792-X"},{"key":"e_1_2_1_8_1","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1093\/oxfordjournals.aje.a112361","article-title":"Limited family clustering of hepatitis B surface antigen in a Melanesian population","volume":"105","author":"Mazzur S","year":"1977","journal-title":"American Journal of Epidemiology"},{"key":"e_1_2_1_9_1","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1128\/iai.32.2.675-680.1981","article-title":"Epidemiology of hepatitis B infection in Liberian infants","volume":"32","author":"Prince AM","year":"1981","journal-title":"Infection and Immunity"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(79)91491-0"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.1890070209"},{"key":"e_1_2_1_12_1","first-page":"297","article-title":"Sociodemographic aspects of the epidemiology of hepatitis B","volume":"310","author":"Szmuness W","year":"1978","journal-title":"Viral Hepatitis"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198010093031501"}],"container-title":["Journal of Medical Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjmv.1890110206","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmv.1890110206","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,19]],"date-time":"2023-10-19T13:59:07Z","timestamp":1697723947000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmv.1890110206"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1983,1]]},"references-count":12,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1983,1]]}},"alternative-id":["10.1002\/jmv.1890110206"],"URL":"https:\/\/doi.org\/10.1002\/jmv.1890110206","archive":["Portico"],"relation":{},"ISSN":["0146-6615","1096-9071"],"issn-type":[{"value":"0146-6615","type":"print"},{"value":"1096-9071","type":"electronic"}],"subject":[],"published":{"date-parts":[[1983,1]]}}}