{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T19:07:54Z","timestamp":1761764874018},"reference-count":20,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2005,12,6]],"date-time":"2005-12-06T00:00:00Z","timestamp":1133827200000},"content-version":"vor","delay-in-days":8375,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[1983,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Using the immunoperoxidase technique and a broadly cross\u2010reactive antiserum which detects infection with any papillomavirus, papillomavirus capsid antigen was demonstrated in 25 of 48 cutaneous papillomas and in two of 38 cutaneous dysplasias. Both positive dysplastic lesions were diagnosed on histopathologic examination as bowenoid papulosis. Antigen\u2010positive cutaneous warts were scattered in all age categories and at all body sites. In addition, there was little variation in antigen expression by morphologic type of wart. Antigen was localized in the nucleus of superficial epithelial cells. The amount of staining was variable, with some warts showing large numbers of stained nuclei. In other warts only isolated cells stained. In both cases of bowenoid papulosis, small foci of positively stained cells were observed. The finding of papillomavirus antigen in two of 21 cases of bowenoid papulosis is suggestive of an etiologic relationship between this lesion and a papillomavirus. An examination of antigen\u2010negative cases of bowenoid papulosis for a papillomavirus genome will be necessary to confirm these results.<\/jats:p>","DOI":"10.1002\/jmv.1890120304","type":"journal-article","created":{"date-parts":[[2007,3,2]],"date-time":"2007-03-02T11:49:00Z","timestamp":1172836140000},"page":"187-193","source":"Crossref","is-referenced-by-count":23,"title":["Immunoperoxidase localization of papillomavirus antigen in cutaneous warts and bowenoid papulosis"],"prefix":"10.1002","volume":"12","author":[{"given":"Lundy","family":"Braun","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evan R.","family":"Farmer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keerti V.","family":"Shah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,12,6]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.1982.92.6.640"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910250509"},{"key":"e_1_2_1_4_1","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1128\/jvi.44.1.393-400.1982","article-title":"Molecular cloning and characterization of human papilloma virus DNA derived from a laryngeal papilloma","volume":"44","author":"Gissman L","year":"1982","journal-title":"Journal of Virology"},{"key":"e_1_2_1_5_1","first-page":"495","article-title":"Immunologic relatedness of papillomaviruses from different species","volume":"64","author":"Jensen AB","year":"1980","journal-title":"J Natl Cancer Inst"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0090-8258(81)90066-4"},{"key":"e_1_2_1_7_1","first-page":"831","article-title":"Confirmation of the papillomavirus etiology of the condylomatous lesions of the cervix by the peroxidase antiperoxidase technique","volume":"66","author":"Morin C","year":"1981","journal-title":"Journal of the National Cancer Institute"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.79.17.5425"},{"key":"e_1_2_1_9_1","first-page":"1043","volume-title":"Origins of Human Cancer","author":"Orth G","year":"1977"},{"key":"e_1_2_1_10_1","first-page":"259","volume-title":"Viruses in Naturally Occurring Cancers","author":"Orth G","year":"1980"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12525394"},{"key":"e_1_2_1_12_1","unstructured":"OrthG personal communication 1982."},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19810801)48:3<820::AID-CNCR2820480325>3.0.CO;2-H"},{"key":"e_1_2_1_14_1","volume-title":"Immunocytochemistry","author":"Sternberger LA","year":"1974"},{"key":"e_1_2_1_15_1","first-page":"92","article-title":"Bowenoid papulosis. A Review","volume":"27","author":"Taylor R","year":"1981","journal-title":"Cutis"},{"key":"e_1_2_1_16_1","first-page":"195","article-title":"Human papillomavirus DNA detected in two verrucous carcinomas","volume":"72","author":"Ubben K","year":"1979","journal-title":"Journal of Investigative Dermatology"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197810)42:4<1890::AID-CNCR2820420430>3.0.CO;2-C"},{"key":"e_1_2_1_18_1","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1001\/archderm.1979.04010030014005","article-title":"Bowenoid papulosis of the genitalia","volume":"115","author":"Wade TR","year":"1979","journal-title":"Archives of Dermatology"},{"key":"e_1_2_1_19_1","first-page":"727","article-title":"Immunological identification of papillomavirus antigen in paraffin\u2010processed condyloma tissues from the female genital tract","volume":"556","author":"Woodruff JD","year":"1980","journal-title":"Obstetrics and Gynecology"},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000372-198000240-00003"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-66800-5_1"}],"container-title":["Journal of Medical Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjmv.1890120304","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmv.1890120304","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,20]],"date-time":"2023-10-20T11:48:30Z","timestamp":1697802510000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmv.1890120304"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1983,1]]},"references-count":20,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1983,1]]}},"alternative-id":["10.1002\/jmv.1890120304"],"URL":"https:\/\/doi.org\/10.1002\/jmv.1890120304","archive":["Portico"],"relation":{},"ISSN":["0146-6615","1096-9071"],"issn-type":[{"value":"0146-6615","type":"print"},{"value":"1096-9071","type":"electronic"}],"subject":[],"published":{"date-parts":[[1983,1]]}}}