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The prevalence of hepatitis B was determined by testing samples from 620 residents. By examining paired serum samples from 79 children and 80 adults, it was determined that new infections occurred during the five years of this study in at least 14 children (18%) (aged 4\u201317 years) and ten adults (12%) (aged 23\u201365 years). These 24 new infections were distributed among 20 households and were not associated with active HBV infections in the mother or, in most cases, other family members. Intervention to prevent hepatitis B in regions such as rural Zambia will require vaccination of susceptible children and adults as well as newborn infants.<\/jats:p>","DOI":"10.1002\/jmv.1890150203","type":"journal-article","created":{"date-parts":[[2007,3,2]],"date-time":"2007-03-02T12:00:16Z","timestamp":1172836816000},"page":"113-120","source":"Crossref","is-referenced-by-count":32,"title":["Horizontal transmission of hepatitis B virus among children and adults in five rural villages in Zambia"],"prefix":"10.1002","volume":"15","author":[{"given":"E.","family":"Tabor","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. 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