{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,8]],"date-time":"2025-04-08T21:39:41Z","timestamp":1744148381933},"reference-count":11,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2005,12,7]],"date-time":"2005-12-07T00:00:00Z","timestamp":1133913600000},"content-version":"vor","delay-in-days":7494,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[1985,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Guinea pig infection with a highly passaged XJ prototype strain of Jun\u00edn virus by the intramuscular route (IM) was carried out in order to study viral tropism modification in this host. The neurotropism of this strain was demonstrated by viral isolation, meningitis, and by the presence of Junin antigens as shown by immunofluorescence. These events, not previously observed with the same lower\u2010passaged strain, revealed the appearance of neurotropism after multiple passages in guinea pigs.<\/jats:p>","DOI":"10.1002\/jmv.1890150208","type":"journal-article","created":{"date-parts":[[2007,3,2]],"date-time":"2007-03-02T12:00:16Z","timestamp":1172836816000},"page":"157-161","source":"Crossref","is-referenced-by-count":8,"title":["Neurotropism of a high\u2010passage XJ strain of jun\u00edn virus"],"prefix":"10.1002","volume":"15","author":[{"given":"Jos\u00e9 R.","family":"Oubi\u00f1a","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guadalupe","family":"Carballal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,12,7]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"284","article-title":"Efecto de la inoculaci\u00f3n intracerebral del virus Jun\u00edn en el cobayo","volume":"42","author":"Boxaca MC","year":"1982","journal-title":"Medicina (Bs. 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Adelantos en Microbiolog\u00eda","volume":"2","author":"Weissenbacher MC","year":"1983","journal-title":"Enfermedades Infecciosas"}],"container-title":["Journal of Medical Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjmv.1890150208","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmv.1890150208","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,19]],"date-time":"2023-10-19T23:21:59Z","timestamp":1697757719000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmv.1890150208"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1985,6]]},"references-count":11,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1985,6]]}},"alternative-id":["10.1002\/jmv.1890150208"],"URL":"https:\/\/doi.org\/10.1002\/jmv.1890150208","archive":["Portico"],"relation":{},"ISSN":["0146-6615","1096-9071"],"issn-type":[{"value":"0146-6615","type":"print"},{"value":"1096-9071","type":"electronic"}],"subject":[],"published":{"date-parts":[[1985,6]]}}}