{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T14:41:46Z","timestamp":1761662506059},"reference-count":25,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2005,12,11]],"date-time":"2005-12-11T00:00:00Z","timestamp":1134259200000},"content-version":"vor","delay-in-days":6980,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[1986,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Approximately 15 to 20% of the general population in Taiwan are chronic hepatitis B surface antigen (HBsAg) carriers. However, the incidence of hepatitis D virus (HDV) infection is low (5\u20138%) in patients with HBsAg\u2010positive chronic liver diseases in this area. To evaluate the prevalence of hepatitis B virus (HBV) and HDV infection among drug abusers in Taiwan, serum samples were collected from 152 drug abusers at the Taipei Municipal Anti\u2010Narcotic Institute and test for HBV and HDV markers. Of these, 24 (15.8%) were HBsAg positive, and only 15 (9.9%) were seronegative for all HBV markers. Of the 115 intravenous drug abusers, serum antibody to hepatitis D antigen (anti\u2010HD) was positive in 78.9% of 19 persons who were HBsAg positive, and in 7.5% of 80 persons who were positive for antibody to HBsAg (anti\u2010HBs). Anti\u2010HD was not detected in the sera from all 37 nonintravenous drug abusers regardless of the status of their HBV markers. Also, none of 63 asymptomatic HBsAg carrier pregnant women or 23 patients with acute type B viral hepatitis had measurable anti\u2010HD in their sera. Thus, the high frequency of HDV detected among Chinese HBsAg carrier intravenous drug abusers in Taiwan is similar to that reported in Western countries.<\/jats:p>","DOI":"10.1002\/jmv.1890200306","type":"journal-article","created":{"date-parts":[[2007,3,2]],"date-time":"2007-03-02T12:51:30Z","timestamp":1172839890000},"page":"247-252","source":"Crossref","is-referenced-by-count":31,"title":["Hepatitis B and D Virus Infection Among Drug Abusers in Taiwan"],"prefix":"10.1002","volume":"20","author":[{"given":"Shou\u2010Dong","family":"Lee","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiin\u2010Yu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaw\u2010Ching","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yang\u2010Te","family":"Tsai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kwang\u2010Juei","family":"Lo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying\u2010Te","family":"Chiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,12,11]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/147.2.185"},{"key":"e_1_2_1_3_1","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1093\/oxfordjournals.aje.a113532","article-title":"Incidence of hepatitis among students at a university in Taiwan","volume":"117","author":"Beasley RP","year":"1983","journal-title":"American Journal of Epidemiology"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.1840040324"},{"key":"e_1_2_1_5_1","first-page":"475","article-title":"Hepatitis B viral markers in patients with primary hepatocellular carcinoma in Taiwan","volume":"66","author":"Chien MC","year":"1981","journal-title":"Journal of National Cancer Institute"},{"key":"e_1_2_1_6_1","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/S0016-5085(83)80243-1","article-title":"Prevalence of delta antibody among chronic hepatitis B virus infected patients in the Los Angeles area: Its correlation with the liver biopsy diagnosis","volume":"85","author":"Govindarajan S","year":"1983","journal-title":"Gastroenterology"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5085(84)80153-5"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.1890140106"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-100-3-339"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/146.4.472"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.1890130404"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.1840050225"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/152.4.817"},{"key":"e_1_2_1_14_1","first-page":"65","article-title":"Combined passive and active immunization for interruption of perinatal transmission of hepatitis B virus in Taiwan","volume":"32","author":"Lo KJ","year":"1985","journal-title":"Hepato\u2010Gastroenterology"},{"key":"e_1_2_1_15_1","first-page":"269","volume-title":"Viral Hepatitis and Delta Infection. 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