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IgM and IgG antibodies to at least 11 structural polypeptides with molecular weights of 28K, 49K. 55K, 57K. &amp;\u20107OK, 82K, 87K, IIOK, 150K. 205K, and 235K were detected in the patients sera in the serum sample obtained in the acute phase of the disease. IgA antibodies to polypeptides with molecular weights of 66\u201070K. 82K. 11OK, and 150K were also detected in these sera. In healthy seropositive adults, IgG antibodies with the same molecular weight polypeptides, excluding the 205K and 235K polypeptides, were detected as in convalescent CMV\u2010MN patients. A prominent reactivity of IgM and IgA antibodies to the 66\u201070K and ISOK polypeptides was noted in the acute sera from all the CMV\u2010MN patients examined, but not in a number of late convalescent sera. The potential implications of these findings in the development of specific serological tests are discussed.<\/jats:p>","DOI":"10.1002\/jmv.1890220305","type":"journal-article","created":{"date-parts":[[2007,3,2]],"date-time":"2007-03-02T13:30:19Z","timestamp":1172842219000},"page":"223-230","source":"Crossref","is-referenced-by-count":21,"title":["Virus\u2010specific serum IgG, IgM, and IgA antibodies in cytomegalovirus mononucleosis patients as determined by immunoblotting technique"],"prefix":"10.1002","volume":"22","author":[{"given":"Avi","family":"Porath","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Negba","family":"Hanuka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arie","family":"Keynan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Israel","family":"Sarov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,12,7]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1159\/000149273"},{"key":"e_1_2_1_3_1","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1128\/jcm.21.4.517-521.1985","article-title":"Antibody response to cytomegalovirus polypeptides captured by monoclonal antibodies on the solid phase in enzyme imniunoassays","volume":"10","author":"Cremer NE","year":"1985","journal-title":"Journal of Clinical Microbiology"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.27.12.1153"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-65-11-1991"},{"key":"e_1_2_1_6_1","doi-asserted-by":"crossref","first-page":"3391","DOI":"10.4049\/jimmunol.134.5.3391","article-title":"A 64.000 dalton matrix protein of human cytomegalovirus induced in vitro immune responses similar to those of whole viral protein","volume":"134","author":"Forman SJ","year":"1985","journal-title":"The Journal of Immunology"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/0042-6822(83)90265-9"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910260105"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1159\/000149177"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01320614"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/0042-6822(83)90122-8"},{"key":"e_1_2_1_12_1","first-page":"49","article-title":"Detection of anti\u2010platelet antibodies in patients with idiopathic thrombocytopenic purpura (ITP) and in patients with rubella and herpes group viral infections","volume":"44","author":"Kahane S","year":"1981","journal-title":"Clinical and Experimental Immunology"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/227680a0"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.1890170403"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/0042-6822(84)90039-4"},{"key":"e_1_2_1_16_1","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1128\/jcm.21.5.800-802.1985","article-title":"Selective reactivity of antibodies to human immunoglobulins G. 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