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Circulating alpha IFN was detected in 50% of the animals from days 2 to 9 postinfection (pi) and in 100% at day 11 pi, when all animals were in the premortem stage.<\/jats:p><jats:p>Individual levels ranged from 20 to 1,280 guinea pig IFN units (GPIFNU)\/ml. A correlation between XJ strain virulence and IFN titers was recorded. A possible role of IFN as a pathogenic factor in the outcome of the disease is discussed.<\/jats:p>","DOI":"10.1002\/jmv.1890240112","type":"journal-article","created":{"date-parts":[[2007,3,2]],"date-time":"2007-03-02T13:49:51Z","timestamp":1172843391000},"page":"97-99","source":"Crossref","is-referenced-by-count":11,"title":["Circulating interferon in the guinea pig infected with the XJ, prototype Jun\u00edn virus strain"],"prefix":"10.1002","volume":"24","author":[{"given":"C. B.","family":"Dejean","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. 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