{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T10:21:47Z","timestamp":1762078907798},"reference-count":7,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2005,12,11]],"date-time":"2005-12-11T00:00:00Z","timestamp":1134259200000},"content-version":"vor","delay-in-days":6037,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[1989,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Shedding of herpes simplex virus type 1 (HSV\u20101) into saliva was studied in 83 patients with orofacial fractures. Infectious virus was isolated from 14 of 83 patients (16.8%) with no detectable herpetic lesion during hospitalization. Of the 83 patients, 44 (53%) had HSV\u20101 specific antibody. Virus shedding into saliva was observed only in the patients with antibody to HSV\u20101; thus, the frequency of virus shedding patients among those with antibody was 31% (14 of 44 patients).<\/jats:p><jats:p>The frequency was obviously higher than that of a healthy population. The period of HSV\u20101 shedding had a mean of 3.7 days with range of 1 to 8 days, which is also significantly longer than that of a healthy population. These results strongly suggest that both treatment and operation lead effectively to reactivation of latently infected HSV\u20101.<\/jats:p>","DOI":"10.1002\/jmv.1890280205","type":"journal-article","created":{"date-parts":[[2007,3,2]],"date-time":"2007-03-02T16:58:22Z","timestamp":1172854702000},"page":"78-80","source":"Crossref","is-referenced-by-count":23,"title":["Shedding of herpes simplex virus type 1 into saliva in patients with orofacial fracture"],"prefix":"10.1002","volume":"28","author":[{"given":"T.","family":"Kameyama","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Futami","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Nakayoshi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Sujaku","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Yamamoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,12,11]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.1890210206"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(74)90085-1"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(76)92024-9"},{"key":"e_1_2_1_5_1","first-page":"397","article-title":"Isolation of herpes simplex virus (type 1) from saliva in patients operated","volume":"34","author":"Kameyama T","year":"1985","journal-title":"Journal of the Japanese Stomatological Society"},{"key":"e_1_2_1_6_1","doi-asserted-by":"crossref","unstructured":"KameyamaT SujakuC YamamotoS HwangC ShillitoeE(1988):Shedding of herpes simplex virus type 1 into saliva in a Japanese population. Journal of Oral Pathology (in press).","DOI":"10.1111\/j.1600-0714.1988.tb01320.x"},{"key":"e_1_2_1_7_1","first-page":"49","article-title":"A clinical and virological study for reactivation of herpes simplex virus type 1","volume":"49","author":"Koga T","year":"1986","journal-title":"Journal of the Kurume Medical Association"},{"key":"e_1_2_1_8_1","first-page":"79","volume-title":"Viral infections in Oral Medicine","author":"Openshaw H","year":"1982"}],"container-title":["Journal of Medical Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjmv.1890280205","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmv.1890280205","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,22]],"date-time":"2023-10-22T14:01:42Z","timestamp":1697983302000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmv.1890280205"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1989,6]]},"references-count":7,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1989,6]]}},"alternative-id":["10.1002\/jmv.1890280205"],"URL":"https:\/\/doi.org\/10.1002\/jmv.1890280205","archive":["Portico"],"relation":{},"ISSN":["0146-6615","1096-9071"],"issn-type":[{"value":"0146-6615","type":"print"},{"value":"1096-9071","type":"electronic"}],"subject":[],"published":{"date-parts":[[1989,6]]}}}