{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T09:20:03Z","timestamp":1784193603687,"version":"3.55.0"},"reference-count":14,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2005,12,7]],"date-time":"2005-12-07T00:00:00Z","timestamp":1133913600000},"content-version":"vor","delay-in-days":5638,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[1990,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Epidemics of acute haemorrhagic conjunctivitis caused by a variant of coxsackievirus A24 (CA24v) and enterovirus 70 (EV70) have occurred periodically in Singapore. A seroepidemiological survey conducted before the CA24v epidemic in 1985 and in the midst of the EV70 epidemic in 1983 showed a neutralising antibody prevalence (\u2a7e 1:4) of 19.1% and 66.9% to CA24v and EV70, respectively. The seropositivity rate to both viruses was highest in children 10\u201314 years of age, but no sex or ethnic difference was noted. It appears from the data that an epidemic could be triggered when the herd immunity of the population falls below a critical level. There was a significant correlation in seroprevalence between CA24v and EV70 (<jats:italic>P<\/jats:italic> = 7.75 \u00d7 10<jats:sup>\u22123<\/jats:sup>).<\/jats:p>","DOI":"10.1002\/jmv.1890310313","type":"journal-article","created":{"date-parts":[[2007,3,2]],"date-time":"2007-03-02T18:41:11Z","timestamp":1172860871000},"page":"245-247","source":"Crossref","is-referenced-by-count":21,"title":["Acute haemorrhagic conjunctivitis: Seroepidemiology of coxsackievirus A24 variant and enterovirus 70 in Singapore"],"prefix":"10.1002","volume":"31","author":[{"given":"K. T.","family":"Goh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P. L.","family":"Ooi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Miyamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Ogino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Yamazaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,12,7]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"1","article-title":"Acute haemorrhagic conjunctivitis in Hong Kong 1971\u20131975","volume":"8","author":"Chang WH","year":"1977","journal-title":"Southeast Asian Journal of Tropical Medicine and Public Health"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/146.1.16"},{"key":"e_1_2_1_4_1","first-page":"225","article-title":"An epidemiological study of five families in the 1975 conjunctivitis epidemic","volume":"17","author":"Goh KT","year":"1976","journal-title":"Singapore Medical Journal"},{"key":"e_1_2_1_5_1","first-page":"83","article-title":"Immune status of the population to poliovirus infection in Singapore","volume":"65","author":"Goh KT","year":"1987","journal-title":"Bulletin of the World Health Organization"},{"key":"e_1_2_1_6_1","first-page":"473","article-title":"An epidemic of acute conjunctivitis caused by enterovirus 70 in Singapore in 1980","volume":"12","author":"Goh KT","year":"1981","journal-title":"Southeast Asian Journal of Tropical Medicine and Public Health"},{"key":"e_1_2_1_7_1","first-page":"235","volume-title":"Acute Haemorrhagic Conjunctivitis: Etiology, Epidemiology and Clinical Manifestations","author":"Hung TP","year":"1989"},{"key":"e_1_2_1_8_1","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1093\/oxfordjournals.aje.a112106","article-title":"Apollo 11 disease or acute haemorrhagic conjunctivitis: A pandemic of a new enterovirus infection of the eyes","volume":"101","author":"Kono R","year":"1975","journal-title":"American Journal of Epidemiology"},{"key":"e_1_2_1_9_1","first-page":"247","article-title":"An epidemic of conjunctivitis in Singapore in 1970","volume":"12","author":"Lim KH","year":"1971","journal-title":"Singapore Medical Journal"},{"key":"e_1_2_1_10_1","first-page":"67","volume-title":"Acute Haemorrhagic Conjunctivitis: Etiology, Epidemiology and Clinical Manifestations","author":"Miyamura K","year":"1989"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.7883\/yoken1952.29.95"},{"key":"e_1_2_1_12_1","volume-title":"Multipurpose Serological Surveys &WHO Serum Reference Banks: Report of a WHO Scientific Group","author":"WHO","year":"1970"},{"key":"e_1_2_1_13_1","first-page":"389","volume-title":"Acute Haemorrhagic Conjunctivitis: Etiology, Epidemiology and Clinical Manifestations","author":"Yamazaki S","year":"1989"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(72)92216-7"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.70.11.869"}],"container-title":["Journal of Medical Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjmv.1890310313","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmv.1890310313","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,22]],"date-time":"2023-10-22T19:42:31Z","timestamp":1698003751000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmv.1890310313"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,7]]},"references-count":14,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1990,7]]}},"alternative-id":["10.1002\/jmv.1890310313"],"URL":"https:\/\/doi.org\/10.1002\/jmv.1890310313","archive":["Portico"],"relation":{},"ISSN":["0146-6615","1096-9071"],"issn-type":[{"value":"0146-6615","type":"print"},{"value":"1096-9071","type":"electronic"}],"subject":[],"published":{"date-parts":[[1990,7]]}}}