{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T04:53:31Z","timestamp":1764996811417},"reference-count":18,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2005,12,7]],"date-time":"2005-12-07T00:00:00Z","timestamp":1133913600000},"content-version":"vor","delay-in-days":5485,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[1990,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Serum hepatitis B virus (HBV) DNA was assayed using polymerase chain reaction, in 107 HBsAg\u2010negative normal Chinese subjects. The results showed that eight subjects (7.5%) had HBV DNA. In the subgroup with antibody to hepatitis B surface antigen (anti\u2010HBs) and to hepatitis B core antigen (anti\u2010HBc), 7.3% (5\/68) were positive for HBV DNA; HBV DNA was not detected in six individuals with anti\u2010HBs only and in nine with anti\u2010HBc only. In four persons with anti\u2010HBc and anti\u2010HBe, one had HBV DNA. In 20 subjects negative for all hepatitis B serological markers, two (10%) were found to have HBV DNA. This study indicates that serological markers are not adequate to rule out HBV infection, and it further implies that present blood donor screening methods may need improving.<\/jats:p>","DOI":"10.1002\/jmv.1890320412","type":"journal-article","created":{"date-parts":[[2007,3,2]],"date-time":"2007-03-02T19:01:46Z","timestamp":1172862106000},"page":"257-260","source":"Crossref","is-referenced-by-count":58,"title":["Serum hepatitis B virus DNA in healthy HBsAg\u2010negative Chinese adults evaluated by polymerase chain 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