{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,5]],"date-time":"2025-04-05T23:25:24Z","timestamp":1743895524848},"reference-count":16,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2005,12,8]],"date-time":"2005-12-08T00:00:00Z","timestamp":1134000000000},"content-version":"vor","delay-in-days":5424,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[1991,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The Oka varicella vaccine strain can be differentiated from wild\u2010type strains by its unique restriction endonuclease fingerprinting (REFP: Hpal\u2010K and EcoRI\u2010P) pattern of the gpV\u2010coding region of the varicella\u2010zoster virus (VZV) genome. VZV\u2010DNAs from patients with complicated clinical courses related to vaccination were examined to determine whether they were vaccine\u2010derived or wild\u2010type. A virus was isolated from a one year\u2010old boy with acute lymphocytic leukemia (ALL) who developed typical varicella 28 days after vaccination (case A). Another virus was isolated from a four\u2010year\u2010old boy without clinical symptoms following household contact with varicella patients at the age of two months, and he developed zoster 14 months after vaccination (case B). Also, two strains (OK1 and OK2) were isolated from household contacts (mother and sister) with a vaccinee with ALL in Oklahoma who developed varicella 18 days after vaccination (case C). In case C, Bgll\u2010REFP did not determine conclusively whether the two strains (OK1 and OK2) were vaccine\u2010derived or wild\u2010type because the patterns obtained were different from both the Oka varicella vaccine strain and American wild\u2010type strains [Gelb et al., Journal of Infectious Diseases, 155:633\u2013640, 1987]. All VZV strains examined in the present study were identified as wild\u2010type by our method using Hpal\u2010K and EcoRI\u2010P fragments as marker fragments. Thus it is becoming evident that REFP using Hpal and EcoRl endonucleases is a convenient and reliable means of distinguishing between the Oka vaccine virus strain and wild\u2010type viruses isolated from individuals developing vesicular rashes shortly and long after varicella vaccination.<\/jats:p>","DOI":"10.1002\/jmv.1890330212","type":"journal-article","created":{"date-parts":[[2007,3,2]],"date-time":"2007-03-02T18:59:11Z","timestamp":1172861951000},"page":"128-132","source":"Crossref","is-referenced-by-count":18,"title":["Differentiation of Oka varicella vaccine strain from wild varicella\u2010zoster virus strains isolated from vaccinees and household contact"],"prefix":"10.1002","volume":"33","author":[{"given":"Kimiyasu","family":"Shiraki","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiyoshi","family":"Horiuchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshizo","family":"Asano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koichi","family":"Yamanishi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michiaki","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,12,8]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-67-9-1759"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.1890240310"},{"key":"e_1_2_1_4_1","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1128\/jvi.40.1.314-318.1981","article-title":"Varicella\u2010zoster virus vaccine differs from the parental virus DNA","volume":"40","author":"Ecker JR","year":"1981","journal-title":"Journal of Virology"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/155.4.633"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/149.2.137"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/160.3.535"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/149.6.956"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-67-9-1817"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4684-5853-4_9"},{"key":"e_1_2_1_11_1","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1159\/000150060","article-title":"Molecular analysis of the thymidine kinase gene of the thymidine kinase\u2010deficient mutants of varicella\u2010zoster virus","volume":"29","author":"Mori H","year":"1988","journal-title":"Intervirology"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(83)91271-0"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-66-2-221"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-64-5-1031"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198411223112107"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(85)80301-2"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-55-1-207"}],"container-title":["Journal of Medical Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjmv.1890330212","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmv.1890330212","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,22]],"date-time":"2023-10-22T23:42:12Z","timestamp":1698018132000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmv.1890330212"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1991,2]]},"references-count":16,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1991,2]]}},"alternative-id":["10.1002\/jmv.1890330212"],"URL":"https:\/\/doi.org\/10.1002\/jmv.1890330212","archive":["Portico"],"relation":{},"ISSN":["0146-6615","1096-9071"],"issn-type":[{"value":"0146-6615","type":"print"},{"value":"1096-9071","type":"electronic"}],"subject":[],"published":{"date-parts":[[1991,2]]}}}