{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,24]],"date-time":"2023-10-24T11:14:18Z","timestamp":1698146058191},"reference-count":11,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2005,12,9]],"date-time":"2005-12-09T00:00:00Z","timestamp":1134086400000},"content-version":"vor","delay-in-days":5213,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[1991,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Hydropenic strain 13 guinea pigs (GP13) injected with Pichind\u00e9 virus show marked jejunal capillary disruption determined by a reduction in protein reflection coefficient (\u03c3) [Katz and Starr, 1990]. These studies examined whether this is reversed by a 2% Ringer's expansion, and whether anorexia may contribute to reduced \u03c3. GP13 were either infected or given a 60% expected ad lib diet, and were studied while under a 2% Ringer's expansion. The results showed 1) infected GP13 separated into groups with either a persistently low u (volume unresponsive) or a normal \u03c3 (volume responsive), but no obvious feature of the animals could predict responsiveness; 2) caloric restriction had minimal to no effect on \u03c3; and 3) both responsive and unresponsive GP had increased heart, lung, and kidney weights. Volume expansion may have salutary effects in some infected GP13, and this is probably due to pressure mediated effects on the capillary wall. The findings support the possibility that conservative management of hemorrhagic fevers may directly ameliorate capillary leak.<\/jats:p>","DOI":"10.1002\/jmv.1890350113","type":"journal-article","created":{"date-parts":[[2007,3,2]],"date-time":"2007-03-02T20:25:25Z","timestamp":1172867125000},"page":"60-64","source":"Crossref","is-referenced-by-count":0,"title":["Influence of volume expansion on capillary transport in the gut of pichind\u00e9 virus infected strain 13 guinea pigs"],"prefix":"10.1002","volume":"35","author":[{"given":"Murray A.","family":"Katz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James F.","family":"Starr","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,12,9]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"94","volume-title":"Statistics for Research","author":"Dowdy S","year":"1983"},{"key":"e_1_2_1_3_1","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1128\/iai.32.2.872-880.1981","article-title":"Pathogenesis of a Pichinde virus strain adapted to produce lethal infections in guinea pigs","volume":"32","author":"Jahrling RB","year":"1981","journal-title":"Infection and Immunity"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5193(85)80293-9"},{"key":"e_1_2_1_5_1","first-page":"417","article-title":"The effect of hydrostatic gradient on solvent drag reflection coefficient in heteroporous membranes: Differences between model\u2010dependent and model\u2010independent computations","volume":"2","author":"Katz MA","year":"1985","journal-title":"Mi\u2010crocirculation, Endothelium, and Lymphatics"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0026-2862(85)90051-2"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/162.6.1304"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-71726-0_2"},{"key":"e_1_2_1_9_1","first-page":"116","volume-title":"Nonparametric Statistics for the Behavioral Sciences","author":"Siegel S","year":"1956"},{"key":"e_1_2_1_10_1","first-page":"467","volume-title":"Handbook of Physiology, Section 2, The Cardiovascular System, Vol. IV, The Microcirculation","author":"Taylor AE","year":"1984"},{"key":"e_1_2_1_11_1","doi-asserted-by":"crossref","first-page":"1574","DOI":"10.1152\/jappl.1981.51.6.1574","article-title":"Deficiencies in pore\u2010membrane models of microvascular fluid and solute transudation","volume":"51","author":"Winn R","year":"1981","journal-title":"Journal of Applied Physiology"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.53.5.622"}],"container-title":["Journal of Medical Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjmv.1890350113","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmv.1890350113","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,23]],"date-time":"2023-10-23T07:37:59Z","timestamp":1698046679000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmv.1890350113"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1991,9]]},"references-count":11,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1991,9]]}},"alternative-id":["10.1002\/jmv.1890350113"],"URL":"https:\/\/doi.org\/10.1002\/jmv.1890350113","archive":["Portico"],"relation":{},"ISSN":["0146-6615","1096-9071"],"issn-type":[{"value":"0146-6615","type":"print"},{"value":"1096-9071","type":"electronic"}],"subject":[],"published":{"date-parts":[[1991,9]]}}}