{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,17]],"date-time":"2023-11-17T18:00:54Z","timestamp":1700244054519},"reference-count":14,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2005,12,7]],"date-time":"2005-12-07T00:00:00Z","timestamp":1133913600000},"content-version":"vor","delay-in-days":4937,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[1992,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Serological markers of hepatitis A, B, and Delta and human immunodeficiency viruses were studied in 25 children receiving cancer chemo\u2010therapy. Eighty\u2010eight percent had pre\u2010existing HAV immunity which was unaltered by chemo\u2010therapy. HDV infection was observed in 8% while HIV was conspicuous by its absence. Active HBV infection, observed in 76% of the children, was asymptomatic in the majority and was accompanied by a high incidence of HBe antigenaemia (57.9%) and its persistence. Pre\u2010existing anti\u2010HBs failed to prevent HBV infection recurrence, which was, however, transient and self\u2010limiting. Multi\u2010ple blood transfusions and repeated parenteral exposures appeared to be the possible sources of HBV acquisition. Transmission to close contacts was also observed. The study suggests that although HBV vaccine might not be protective against HBV infection in patients receiving cancer chemotherapy, it may prevent its persistence and thereby help in reducing chronic liver dis\u2010ease\u2010related morbidity and a highly infectious reservoir. Strict HBV screening of blood donors, exclusive use of disposable equipment, and vac\u2010cination of close contacts of cancer patients is recommended, particularly in HBV endemic third\u2010world countries. \u00a9 1992 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/jmv.1890370202","type":"journal-article","created":{"date-parts":[[2007,3,2]],"date-time":"2007-03-02T21:28:05Z","timestamp":1172870885000},"page":"83-86","source":"Crossref","is-referenced-by-count":6,"title":["Infection with hepatitis A, B, Delta, And human immunodeficiency viruses in children receiving cycled cancer chemotherapy"],"prefix":"10.1002","volume":"37","author":[{"given":"Archana","family":"Kumar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. K.","family":"Misra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. 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A serologic study of patients and staff in a pediatric oncology unit","volume":"61","author":"Tabor E","year":"1978","journal-title":"Pediatrics"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(82)80431-9"},{"key":"e_1_2_1_15_1","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/S0016-5085(75)80054-0","article-title":"Serial studies of hepatitis associated antigen and antibody in patients receiving anti tumor chemotherapy for myeloproliferative and lymphoprolif\u2010erative disorders","volume":"68","author":"Wands JR","year":"1975","journal-title":"Gastroenterology"}],"container-title":["Journal of Medical Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjmv.1890370202","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmv.1890370202","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,23]],"date-time":"2023-10-23T15:16:53Z","timestamp":1698074213000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmv.1890370202"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,6]]},"references-count":14,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1992,6]]}},"alternative-id":["10.1002\/jmv.1890370202"],"URL":"https:\/\/doi.org\/10.1002\/jmv.1890370202","archive":["Portico"],"relation":{},"ISSN":["0146-6615","1096-9071"],"issn-type":[{"value":"0146-6615","type":"print"},{"value":"1096-9071","type":"electronic"}],"subject":[],"published":{"date-parts":[[1992,6]]}}}