{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T13:38:22Z","timestamp":1791725902586,"version":"4.3.4"},"reference-count":17,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2005,12,7]],"date-time":"2005-12-07T00:00:00Z","timestamp":1133913600000},"content-version":"vor","delay-in-days":4511,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[1993,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Immunological and virological evidence for persistence of Japanese encephalitis virus (JEV) in the human nervous system is described in 16\/323 (5%) laboratory\u2010confirmed cases of Japanese encephalitis. In 9\/16 patients, JEV specific IgM antibodies were detected in the CSF even at 50\u2013180 days after the onset of symptoms. Similarly, in 7\/16 patients, apart from IgM antibodies, viral antigen was also present in the CSF beyond the third week of illness and in one patient it could be detected even at 117 days. Infectious virus could be isolated from the CSF beyond the third week of illness in 3\/16 patients. In one patient, JEV was isolated from the CSF on three consecutive occasions at 90, 110, and 117 days after onset of clinical symptoms. These findings suggest that JEV persists in the nervous system of a small proportion of patients. \u00a9 1993 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/jmv.1890400412","type":"journal-article","created":{"date-parts":[[2007,3,2]],"date-time":"2007-03-02T22:38:43Z","timestamp":1172875123000},"page":"326-329","source":"Crossref","is-referenced-by-count":91,"title":["Persistence of Japanese encephalitis virus in the human nervous system"],"prefix":"10.1002","volume":"40","author":[{"given":"V.","family":"Ravi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anita S.","family":"Desai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Poornima 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