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Sera from 161 patients with infectious mononucleosis caused by EBV and 178 age\u2010matched controls were tested for HSV\u2010 and VZV\u2010specific IgA. 98.7 percent of VZV\u2010IgG\u2010positive controls were negative for VZV\u2010IgA, pointing to the stringent control of latent VZV in healthy individuals. During acute EBV infection, 33.8% of VZV\u2010IgG\u2010positive infectious mononucleosis patients produced VZV\u2010specific IgA. This result may be explained either by reactivation of VZV due to transient suppression of cellular immune functions during acute EBV infection or by polyclonal stimulation caused by EBV. Due to the high incidence of HSV\u2010IgA in healthy HSV\u2010IgG\u2010positive individuals, only a marginal effect of acute EBV infection on the appearance of HSV\u2010specific IgA was found. \u00a9 1994 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/jmv.1890440308","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T00:29:49Z","timestamp":1172881789000},"page":"258-262","source":"Crossref","is-referenced-by-count":11,"title":["Activation of a varicella\u2010zoster virus\u2010specific IgA response during acute Epstein\u2010Barr virus infection"],"prefix":"10.1002","volume":"44","author":[{"given":"Wolfgang","family":"Karner","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georg","family":"Bauer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,12,7]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"crossref","unstructured":"AnderssonA VetterV KreutzerL BauerG(1994):The avidities of IgG directed against viral capsid antigen (VCA) or early antigen (EA): Useful markers for a more significant Epstein\u2010Barr virus serology. 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