{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T10:37:52Z","timestamp":1791196672741,"version":"4.1.0"},"reference-count":34,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2007,3,26]],"date-time":"2007-03-26T00:00:00Z","timestamp":1174867200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2007,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Pediatric gastroenteritis is a major cause of childhood morbidity and mortality worldwide, especially in developing countries. It has been increasingly recognised that human caliciviruses (HuCV), comprising noroviruses (NoV), and sapoviruses (SaV), are important in both outbreak and non\u2010outbreak settings. This study aimed to characterise caliciviruses detected in the faeces of hospitalized children and children in the community in India. This study examined 350 faecal samples from children presenting to the hospital with acute gastroenteritis and 673 samples collected from children in the community, 500 from children with diarrhea, and 173 samples from children without diarrhea. Strain characterisation was performed by reverse transcription\u2010polymerase chain reaction (RT\u2010PCR) and partial sequencing of the gene encoding the RNA\u2010dependent RNA polymerase (RdRp) and\/or a region spanning the open reading frames (ORFs) 1 and 2 (ORF1\/ORF2) junction. A total of 68 of 350 specimens (19.4%) from hospitalized children were positive, and SaV and NoV accounted for 5.1 and 15.1% of the infections, respectively. Mixed infections of HuCVs with other enteric pathogens were seen in 9.4% of the total children tested. Sixty\u2010eight out of 673 (10.1%) samples collected from children in the community were positive for caliciviruses, and SaV and NoV accounted for 3.4 and 6.6% of the infections. In the community cohort 55\/500 (11%) and 13\/173 (7.5%) were from symptomatic and asymptomatic children, respectively, and SaVs accounted for 17\/500 (3.4%) and NoVs for 38\/500 (7.6%) of the symptomatic infections. This is the first report of genotyping of circulating caliciviruses in both hospital and community in India and has increased the evidence for the role of these viruses in pediatric gastroenteritis in India. J. Med. Virol. 79:544\u2013551, 2007. \u00a9 2007 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/jmv.20862","type":"journal-article","created":{"date-parts":[[2007,3,26]],"date-time":"2007-03-26T20:19:24Z","timestamp":1174940364000},"page":"544-551","source":"Crossref","is-referenced-by-count":88,"title":["Human caliciviruses in symptomatic and asymptomatic infections in children in Vellore, South India"],"prefix":"10.1002","volume":"79","author":[{"given":"Bindhu","family":"Monica","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sasirekha","family":"Ramani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Indrani","family":"Banerjee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beryl","family":"Primrose","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miren","family":"Iturriza\u2010Gomara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher I.","family":"Gallimore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David W.","family":"Brown","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fathima","family":"M","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prabhakar D.","family":"Moses","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James J.","family":"Gray","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gagandeep","family":"Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,3,26]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01309781"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.14.1.15-37.2001"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01882-05"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.77.21.11603-11615.2003"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.28.3.495-503.1990"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.44.2.327-333.2006"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/154.7.666"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.20488"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1086\/314525"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00705-004-0296-9"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.20592"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.10145"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.1890470416"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1086\/315591"},{"key":"e_1_2_1_16_1","doi-asserted-by":"crossref","first-page":"26","DOI":"10.4269\/ajtmh.1994.51.26","article-title":"Twelve messages from enteric infections for science and society","volume":"51","author":"Guerrant RL","year":"1994","journal-title":"Am J Trop Med Hyg"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.42.3.1305-1307.2004"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00705-004-0345-4"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid1101.040337"},{"key":"e_1_2_1_20_1","doi-asserted-by":"crossref","first-page":"6527","DOI":"10.1128\/jvi.66.11.6527-6532.1992","article-title":"Expression, self\u2010assembly and antigenicity of the Norwalk virus capsid protein","volume":"66","author":"Jiang X","year":"1992","journal-title":"J Virol"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1006\/viro.1993.1345"},{"key":"e_1_2_1_22_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.41.4.1548-1557.2003"},{"key":"e_1_2_1_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0035-9203(00)90231-1"},{"key":"e_1_2_1_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0166-0934(01)00404-9"},{"key":"e_1_2_1_25_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.8380940"},{"key":"e_1_2_1_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2005.04.007"},{"key":"e_1_2_1_27_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid0901.020184"},{"key":"e_1_2_1_28_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.spid.2004.07.004"},{"key":"e_1_2_1_29_1","doi-asserted-by":"publisher","DOI":"10.1086\/314783"},{"key":"e_1_2_1_30_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006454-199905000-00005"},{"key":"e_1_2_1_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00705-005-0514-0"},{"key":"e_1_2_1_32_1","doi-asserted-by":"publisher","DOI":"10.3109\/00365549009027046"},{"key":"e_1_2_1_33_1","doi-asserted-by":"publisher","DOI":"10.1007\/s007050050020"},{"key":"e_1_2_1_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jviromet.2003.08.009"},{"key":"e_1_2_1_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2005.11.015"}],"container-title":["Journal of Medical Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjmv.20862","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmv.20862","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,15]],"date-time":"2023-11-15T10:16:05Z","timestamp":1700043365000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmv.20862"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,3,26]]},"references-count":34,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2007,5]]}},"alternative-id":["10.1002\/jmv.20862"],"URL":"https:\/\/doi.org\/10.1002\/jmv.20862","archive":["Portico"],"relation":{},"ISSN":["0146-6615","1096-9071"],"issn-type":[{"value":"0146-6615","type":"print"},{"value":"1096-9071","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,3,26]]}}}