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In this study it was shown that patients (n\u2009=\u200962) with selective IgA deficiency (IgA\u2010D) (&lt;0.05 g\/L) resolve rotavirus disease and show higher total IgG and IgG1 subclass antibody titers to rotavirus than IgA proficient individuals (n\u2009=\u200962) (geometric mean titer, GMT) 18,101 vs. 4,000 (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.005); 8,463 vs. 1691, (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.005). It is concluded that IgA is not essential for resolving rotavirus disease in humans. J. Med. Virol. 80:531\u2013535, 2008. \u00a9 2008 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/jmv.21101","type":"journal-article","created":{"date-parts":[[2008,1,19]],"date-time":"2008-01-19T01:47:54Z","timestamp":1200707274000},"page":"531-535","source":"Crossref","is-referenced-by-count":23,"title":["Individuals with selective IgA deficiency resolve rotavirus disease and develop higher antibody titers (IgG, IgG1) than IgA competent 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