{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T13:26:21Z","timestamp":1780320381302,"version":"3.54.1"},"reference-count":32,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2008,6,12]],"date-time":"2008-06-12T00:00:00Z","timestamp":1213228800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2008,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The evidence on genotype\u2010specific risk in women infected with human papillomavirus (HPV) with normal cytology and the importance of the distinction of high\u2010risk (HR)\u2010HPV genotypes in the management of low\u2010grade lesions suggest that the distinction of HR\u2010HPV genotypes has the potential to improve the follow\u2010up of patients treated for high\u2010grade cervical lesions. The aims of this study were to define the persistence of the different HR\u2010HPV in the follow\u2010up of surgical treated women, to detect the changes of genotypes from the pre\u2010 to the post\u2010operative status, and to evaluate whether genotype\u2010specific persistence can predict the development of residual or recurrent disease during the follow\u2010up. HR\u2010HPV detection and genotyping was carried out by the Linear Array HPV Genotyping Test\u00ae on cervical cytological samples from 72 women treated by surgery. The 6\u2010month post\u2010operative HPV status was correlated with the pre\u2010operative HPV genotype and with the residual or recurrent disease within 24 months. It was observed that the residual or recurrent disease in women with persistence of HPV 16 and\/or HPV 18 was higher (82.4%) than in women with persistence of at least one HR\u2010HPV type of group 2 (HPV 31, 33, 35, 45, 52, and 58) (66.7%) and at least one type of group 3 (HPV 39, 51, 56, 59, 68, 26, 53, 66, 73, and 82) (14.3%). These data defined HR\u2010HPV groups for the risk of progression of disease and suggested that the identification of persistent infection with different HR\u2010HPV genotypes has the potential to improve the management of these patients. J. Med. Virol. 80:1434\u20131440, 2008. \u00a9 2008 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/jmv.21198","type":"journal-article","created":{"date-parts":[[2008,6,12]],"date-time":"2008-06-12T21:50:07Z","timestamp":1213307407000},"page":"1434-1440","source":"Crossref","is-referenced-by-count":42,"title":["Correlation of high\u2010risk human papillomavirus genotypes persistence and risk of residual or recurrent cervical disease after surgical treatment"],"prefix":"10.1002","volume":"80","author":[{"given":"Simona","family":"Venturoli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simone","family":"Ambretti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica","family":"Cricca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisa","family":"Leo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvano","family":"Costa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica","family":"Musiani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marialuisa","family":"Zerbini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2008,6,12]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2006.04.016"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-8258(03)00435-9"},{"key":"e_1_2_1_4_1","first-page":"3733","article-title":"Is therapeutic conization sufficient to eliminate a high\u2010risk HPV infection of the uterine cervix? 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