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Paired plasma and cellular samples from HIV\u2010negative blood donors, asymptomatic HIV and symptomatic\/AIDS cohorts were screened by multiplex PCR then qPCR for parvovirus B19 (B19V), hepatitis B virus (HBV), GB virus\u2010C (GBV\u2010C), cytomegalovirus (CMV), Epstein\u2013Barr virus (EBV), human herpesvirus\u20108 (HHV\u20108) and varicella\u2010zoster virus (VZV). IgG antibodies specific to each target virus were tested to determine exposure rates. No evidence of viraemia was found for B19V and VZV in any group. Prevalence of GBV\u2010C plasma viraemia was significantly higher in asymptomatic and symptomatic HIV infection (16.7%) and (16.2%) than in blood donors (4%) <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.005. Occult HBV infection was significantly more frequent in symptomatic HIV infection (10.9%) compared to asymptomatic HIV (3.6%) and blood donors (1.6%) <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.005. Although there was a high background of EBV viraemia in cellular fractions of blood donors (8.3%), it was significantly higher in asymptomatic (44.6%) and symptomatic HIV (14.6%) <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.0001. For CMV, the significantly increased prevalence of viraemia was only observed in the plasma fraction of the symptomatic HIV\u20101\/AIDS patients (7.6%) compared to asymptomatic individuals (1.8%) and blood donors (0.8%) <jats:italic>P<\/jats:italic>\u2009\u2264\u20090.001. The background seroprevalence in blood donors was high for B19V (\u226564%), HBV (\u226570%), CMV and EBV (\u226590%) and was significantly increased in HIV infections for HBV, CMV, VZV (symptomatic HIV), and HHV\u20108 (asymptomatic and symptomatic HIV). J. Med. Virol. 81:1860\u20131868, 2009. \u00a9 2009 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/jmv.21614","type":"journal-article","created":{"date-parts":[[2009,9,22]],"date-time":"2009-09-22T23:49:06Z","timestamp":1253663346000},"page":"1860-1868","source":"Crossref","is-referenced-by-count":45,"title":["Prevalence of persistent and latent viruses in untreated patients infected with HIV\u20101 from Ghana, West Africa"],"prefix":"10.1002","volume":"81","author":[{"given":"Lara 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