{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,19]],"date-time":"2026-07-19T05:15:42Z","timestamp":1784438142159,"version":"3.55.0"},"reference-count":44,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2011,2,23]],"date-time":"2011-02-23T00:00:00Z","timestamp":1298419200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2011,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The prevalence of different genotypes of hepatitis C virus (HCV) in Ethiopia is not known. HCV genotypes influence the response to therapy with alpha\u2010interferon alone or in combination with ribavirin. A cross sectional study was conducted on attendees of voluntary counseling and testing center. Serum samples from 1,954 (734 HIV positive and 1,220 HIV negative) individuals were screened for HCV antibody. Active HCV infection was confirmed by quantitative PCR in 18 of the 71 samples with anti\u2010HCV antibodies. The HCV viral load ranged from 39,650 to 9,878,341\u2009IU\/ml (median 1,589,631\u2009IU\/ml) with no significant difference [<jats:italic>\u03c7<\/jats:italic><jats:sup>2<\/jats:sup>(17)\u2009=\u200918.00, <jats:italic>P\u2009<\/jats:italic>=\u20090.389] between persons positive or negative for HIV. The viral load of HCV was, however, higher in older study subjects (r\u2009=\u20090.80, <jats:italic>P\u2009<\/jats:italic>=\u20090.000). HCV genotypes were determined using the VERSANT HCV Genotype Assay (LiPA) and sequence analysis of the NS5b region of the HCV genome. Diverse HCV genotypes were found including genotypes 1, 2, 4, and 5. There was no difference in the distribution regarding the HIV status. As in other parts of the world, genotyping of HCV must be considered whenever HCV is incriminated as a cause of hepatitis. J. Med. Virol. 83:776\u2013782, 2011. \u00a9 2011 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/jmv.21788","type":"journal-article","created":{"date-parts":[[2011,2,25]],"date-time":"2011-02-25T21:23:10Z","timestamp":1298668990000},"page":"776-782","source":"Crossref","is-referenced-by-count":14,"title":["Genotypes and viral load of hepatitis C virus among persons attending a voluntary counseling and testing center in Ethiopia"],"prefix":"10.1002","volume":"83","author":[{"given":"Tesfay","family":"Abreha","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yimtubezinash","family":"Woldeamanuel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Corinna","family":"Pietsch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melanie","family":"Maier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Asrat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Almaz","family":"Abebe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bereket","family":"Hailegiorgis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abraham","family":"Aseffa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uwe Gerd","family":"Liebert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,2,23]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(90)93139-G"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1348-0421.2006.tb03813.x"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2005.11.004"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199908193410802"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1746.2000.02110.x"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-144-10-200605160-00004"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.10164"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/25.3.674"},{"key":"e_1_2_5_10_1","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1097\/00126334-200104010-00008","article-title":"Effect of coexisting HIV\u20101 infection on the diagnosis and evaluation of hepatitis C virus","volume":"26","author":"Bonacini M","year":"2001","journal-title":"J Acquir Immune Defic Syndr"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.02463-05"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.40.9.3127-3134.2002"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-140-6-200403160-00014"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8278(99)80370-5"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1053\/jhep.2001.29201"},{"key":"e_1_2_5_16_1","first-page":"602","article-title":"Natural history of hepatitis C virus infection in multitransfused hemophiliacs: Effect of coinfection with human immunodeficiency virus. 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