{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T11:57:33Z","timestamp":1790855853156,"version":"4.1.0"},"reference-count":45,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2011,5,12]],"date-time":"2011-05-12T00:00:00Z","timestamp":1305158400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2011,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The epidemiology and clinical outcomes of acute hepatitis C are different geographically. This study aimed to investigate the mode of infection, clinical characteristics, and outcomes of acute hepatitis C in Korea. Forty\u2010seven patients with acute hepatitis C were enrolled consecutively in a study conducted in seven medical centers. The patients with the mean age of 45.8 years had mostly mild symptoms. A healthcare\u2010related procedure was the most common exposure history (42.5%): acupuncture (17%), surgery (10.6%), needle\u2010stick injury (8.5%), and other medical procedures (6.4%). There was no case of intravenous drug use. Twenty\u2010one patients (44.7%) recovered spontaneously. Among the 16 patients who received antiviral therapy (34%), all of the 12 evaluable patients had a sustained virologic response, while 10 patients (21.3%) who did not receive antiviral therapy progressed to chronic infection. The overall seroconversion rate of anti\u2010HCV antibody was 61.7%. The patients who recovered spontaneously had significantly lower rate of seroconversion compared with the patients who did not clear spontaneously the infection. In conclusion, acute hepatitis C in Korea was related to various healthcare procedures, including acupuncture, characterized by high rates of spontaneous recovery and low rates of seroconversion, which may be associated with different modes of infection and ethnic differences. The characteristics of acute hepatitis C in Asian countries warrants further study. J. Med. Virol. 83:1195\u20131202, 2011. \u00a9 2011 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/jmv.22100","type":"journal-article","created":{"date-parts":[[2011,5,12]],"date-time":"2011-05-12T20:43:43Z","timestamp":1305233023000},"page":"1195-1202","source":"Crossref","is-referenced-by-count":13,"title":["Acute hepatitis C in Korea: Different modes of infection, high rate of spontaneous recovery, and low rate of seroconversion"],"prefix":"10.1002","volume":"83","author":[{"given":"Jong Yeop","family":"Kim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji Eon","family":"Won","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sook\u2010Hyang","family":"Jeong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang Jong","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seong Gyu","family":"Hwang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sook\u2010Kyoung","family":"Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Si Hyun","family":"Bae","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young Seok","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han Chu","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,5,12]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199908193410802"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00042737-200510000-00013"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.21902"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2893.1999.00153.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.aids.0000189847.98569.2d"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2003.18.5.756"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1074-7613(00)80044-8"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1086\/428578"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199208063270601"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature08309"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1053\/jhep.2003.50019"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.2064"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.21197"},{"key":"e_1_2_6_15_1","first-page":"105","article-title":"Natural history of acute symptomatic hepatitis C in Korea","volume":"46","author":"Kim KA","year":"2005","journal-title":"Korean J Gastroenterol"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2009.03026.x"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2006.74.1117"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200107053450107"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.191.9.1499"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2010.00960.x"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.20103"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)61116-2"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1128\/CDLI.8.4.690-694.2001"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2007.01431.x"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2007.01431.x"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1086\/322619"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2893.2007.00900.x"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1053\/jhep.2001.22112"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.10295"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2007.06.059"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2004.11.021"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(99)00374-5"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0042-6822(03)00461-6"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(05)70216-4"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2004.11.059"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1159\/000087258"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-6-6"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2003.037788"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9071(199911)59:3<290::AID-JMV5>3.0.CO;2-R"},{"key":"e_1_2_6_40_1","doi-asserted-by":"publisher","DOI":"10.1038\/75063"},{"key":"e_1_2_6_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cld.2005.05.003"},{"key":"e_1_2_6_42_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.284.4.450"},{"key":"e_1_2_6_43_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2010.07.005"},{"key":"e_1_2_6_44_1","doi-asserted-by":"publisher","DOI":"10.1086\/379255"},{"key":"e_1_2_6_45_1","first-page":"1","article-title":"Surveillance for acute viral hepatitis\u2014United States, 2006","volume":"57","author":"Wasley A","year":"2008","journal-title":"MMWR Surveill Summ"},{"key":"e_1_2_6_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2005.04.007"}],"container-title":["Journal of Medical Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjmv.22100","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmv.22100","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,21]],"date-time":"2023-11-21T06:26:15Z","timestamp":1700547975000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmv.22100"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,5,12]]},"references-count":45,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2011,7]]}},"alternative-id":["10.1002\/jmv.22100"],"URL":"https:\/\/doi.org\/10.1002\/jmv.22100","archive":["Portico"],"relation":{},"ISSN":["0146-6615","1096-9071"],"issn-type":[{"value":"0146-6615","type":"print"},{"value":"1096-9071","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,5,12]]}}}