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This study aimed to investigate the incidence of herpes simplex virus types\u20101 (HSV\u20101) and 2 (HSV\u20102), varicella\u2010zoster virus (VZV), cytomegalovirus (CMV), human herpesvirus 6 (HHV\u20106) and human enteroviruses (EVs) in cerebrospinal fluid (CSF) samples of Tunisian immunocompetent patients with neuromeningeal disorders. The patients had been hospitalized at the Fattouma Bourguiba University Hospital (Monastir, Tunisia) between September 2007 and June 2009. At least one viral genome was detected in 58 (46%) out of 126 CSF samples collected. Enterovirus was detected in 31 of the positive samples (53.4%), CMV in 20 (34.5%), HSV\u20101 in 3 (5.2%), HSV\u20102 in 6 (10.3%), VZV in 4 (6.9%), HHV\u20106 in 2 (3.4%). More than one viral genome was detected in seven CSF samples, including CMV DNA in six of the samples. The high frequency of enteroviral infections in aseptic meningitis was confirmed. The detection of CMV DNA only suggests a direct role of this virus in the etiology of acute neuromeningeal disorder. J. Med. Virol. 84:282\u2013289, 2012. \u00a9 2011 Wiley Periodicals, Inc.<\/jats:p>","DOI":"10.1002\/jmv.23192","type":"journal-article","created":{"date-parts":[[2011,12,14]],"date-time":"2011-12-14T14:21:31Z","timestamp":1323872491000},"page":"282-289","source":"Crossref","is-referenced-by-count":24,"title":["Detection of herpes simplex virus (1 and 2), varicella\u2010zoster virus, cytomegalovirus, human herpesvirus 6 and enterovirus in immunocompetent tunisian patients with acute neuromeningeal disorder"],"prefix":"10.1002","volume":"84","author":[{"given":"Imen","family":"Nahdi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanen","family":"Boukoum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abid","family":"Nabil Ben Salem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fouad","family":"Ben 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