{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T19:56:46Z","timestamp":1762459006191},"reference-count":26,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2012,7,18]],"date-time":"2012-07-18T00:00:00Z","timestamp":1342569600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2012,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Anal cancer is a rare disease. Nevertheless, it may be a reason for concern among groups in which its incidence is increasing: those who engage in anoreceptive intercourse, promiscuous persons, and those with sexually transmitted infections (HPV and HIV). The aim of this study was to evaluate the prevalence of abnormal anal cytology in women infected with HIV seen at Hospital de Cl\u00ednicas de Porto Alegre, Brazil. A cross\u2010sectional design was used. Anal smear screening was offered to all women infected with HIV seen at the hospital's outpatient sexually transmitted infections clinic from March 2006 to March 2008. A total of 184 patients were thus enrolled. Only patients who gave written consent were included in the study. The prevalence of abnormal anal cytology was 14.1% (26 patients). Twenty\u2010two patients presented atypical squamous cells of undetermined significance, and four exhibited low\u2010grade intraepithelial neoplasia. Initially, abnormal anal cytology was significantly associated with age, number of pregnancies, smoking, abnormal cervical cytology, CD4<jats:sup>+<\/jats:sup>\u2009&lt;\u2009200\u2009cells\/mm<jats:sup>3<\/jats:sup> and hepatitis C co\u2010infection. After adjustment, only CD4<jats:sup>+<\/jats:sup>\u2009&lt;\u2009200\u2009cells\/mm<jats:sup>3<\/jats:sup> and smoking were found to increase the risk of altered anal cytology. The anal Pap method described is simple and can be used for screening in cohorts of HIV\u2010positive women who are at risk of developing anal carcinoma, mainly those with CD4<jats:sup>+<\/jats:sup> counts &lt;200\u2009cells\/mm<jats:sup>3<\/jats:sup> and smokers. J. Med. Virol. 84:1335\u20131339, 2012. \u00a9 2012 Wiley Periodicals, Inc.<\/jats:p>","DOI":"10.1002\/jmv.23346","type":"journal-article","created":{"date-parts":[[2012,7,23]],"date-time":"2012-07-23T19:52:20Z","timestamp":1343073140000},"page":"1335-1339","source":"Crossref","is-referenced-by-count":12,"title":["Prevalence of abnormal anal cytology in women infected with HIV"],"prefix":"10.1002","volume":"84","author":[{"given":"Eunice Beatriz Martin","family":"Chaves","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helo\u00edsa","family":"Folgierini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edison","family":"Capp","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helena","family":"von Eye Corleta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,7,18]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/1742-6413-2-4"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1155\/IDOG\/2006\/40470"},{"key":"e_1_2_6_4_1","unstructured":"Brasil Minist\u00e9rio da Sa\u00fade Coordena\u00e7\u00e3o Nacional de DST\/AIDS. 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