{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T19:15:09Z","timestamp":1791314109898,"version":"4.3.1"},"reference-count":40,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2012,10,23]],"date-time":"2012-10-23T00:00:00Z","timestamp":1350950400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2013,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Community\u2010acquired pneumonia is a major cause of morbidity and mortality in children worldwide. However, few studies have been conducted on the infection of human metapneumovirus (hMPV) associated with pediatric community\u2010acquired pneumonia in China. Nasopharyngeal aspirates were collected between July 2008 and June 2010 from 1,028 children, aged \u226416.5 years, who were diagnosed with community\u2010acquired pneumonia in Beijing, China. Reverse\u2010transcriptase polymerase chain reaction was used to screen the samples for hMPV and common respiratory viruses. hMPV was detected in 6.3% of the patients with community\u2010acquired pneumonia. This detection rate is the third highest for a respiratory virus in children with community\u2010acquired pneumonia, after that of rhinovirus (30.9%) and respiratory syncytial virus (30.7%). The detection rate of hMPV in 2008\/2009 (42\/540, 7.8%) was significantly higher than in 2009\/2010 (23\/488, 4.7%; \u03c7<jats:sup>2<\/jats:sup>\u2009=\u20094.065, <jats:italic>P<\/jats:italic>\u2009=\u20090.044). The hMPV subtypes A2, B1, and B2 were found to co\u2010circulate, with A2 being most prevalent. These results indicate that hMPV plays a substantial role in pediatric community\u2010acquired pneumonia in China. Overall, these findings provide a better understanding of the epidemiological and clinical features of hMPV infections. J. Med. Virol. 85:138\u2013143, 2012. \u00a9 2012 Wiley Periodicals, Inc.<\/jats:p>","DOI":"10.1002\/jmv.23438","type":"journal-article","created":{"date-parts":[[2012,10,23]],"date-time":"2012-10-23T15:43:32Z","timestamp":1351007012000},"page":"138-143","source":"Crossref","is-referenced-by-count":25,"title":["Human metapneumovirus associated with community\u2010acquired pneumonia in children in Beijing, China"],"prefix":"10.1002","volume":"85","author":[{"given":"Guilan","family":"Lu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianguo","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhengde","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunyan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guy","family":"Vernet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kunling","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianwei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,10,23]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-1702(03)00065-0"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)16357-5"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid0906.030017"},{"key":"e_1_2_6_5_1","first-page":"71","article-title":"DNASTAR's Lasergene sequence analysis software","volume":"132","author":"Burland TG","year":"2000","journal-title":"Methods Mol Biol"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e318162a164"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.21264"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.21129"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.21271"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1086\/382482"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.20456"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid1201.050772"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1080\/00365540903148264"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2010.25.3.342"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00705-009-0492-8"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2011.10.011"},{"key":"e_1_2_6_17_1","first-page":"683","article-title":"Human metapneumovirus and community\u2010acquired pneumonia in children","volume":"28","author":"Lin PY","year":"2005","journal-title":"Chang Gung Med J"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.41.7.2987-2991.2003"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e3181c2a1b9"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra011994"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid1004.030555"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a113061"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1750-2659.2011.00206.x"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.21436"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid0906.030009"},{"key":"e_1_2_6_26_1","first-page":"196","article-title":"Community\u2010acquired pneumonia","volume":"77","author":"Polverino E","year":"2011","journal-title":"Minerva Anestesiol"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2009.02746.x"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(10)60060-8"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(10)61459-6"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mcp.0000159831.82529.85"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid0809.020084"},{"key":"e_1_2_6_32_1","first-page":"83","article-title":"Guidelines for management of childhood community\u2010acquired pneumonia (for trial implementation) (I)","volume":"45","year":"2007","journal-title":"Chin J Pediatr"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1038\/89098"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1006\/viro.2001.1355"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid1004.030393"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00705-008-0242-3"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-011-1159-4"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa025472"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2009.07.014"},{"key":"e_1_2_6_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2010.07.013"},{"key":"e_1_2_6_41_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e3181b56009"}],"container-title":["Journal of Medical Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjmv.23438","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmv.23438","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,22]],"date-time":"2023-11-22T12:45:01Z","timestamp":1700657101000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmv.23438"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,10,23]]},"references-count":40,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,1]]}},"alternative-id":["10.1002\/jmv.23438"],"URL":"https:\/\/doi.org\/10.1002\/jmv.23438","archive":["Portico"],"relation":{},"ISSN":["0146-6615","1096-9071"],"issn-type":[{"value":"0146-6615","type":"print"},{"value":"1096-9071","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,10,23]]}}}