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To evaluate the putative role of HPV infection in esophageal adenocarcinoma, 57 formalin\u2010fixed, paraffin\u2010embedded esophageal adenocarcinoma specimens were collected from four hospitals in Shanghai and Anyang, China, between 1999 and 2008. HPV DNA was analyzed using PCR with multiple sets of consensus primers for HPV, GP5+\/6+, CPI\/CPIIG, SPF<jats:sub>10<\/jats:sub>, pU\u20101M\/pU2R, and pU31B\/pU2R. Glyceraldehyde\u20103\u2010phosphate dehydrogenase (GAPDH), the internal control, was amplified successfully in all 57 specimens. However, HPV amplification was not detected in any specimens with any of the consensus primer sets used. The present study indicates that HPV infection is not likely to be a major factor in the etiology of esophageal adenocarcinoma in the Chinese population. J. Med. Virol. 85: 1053\u20131057, 2013. \u00a9 2013 Wiley Periodicals, Inc.<\/jats:p>","DOI":"10.1002\/jmv.23468","type":"journal-article","created":{"date-parts":[[2013,4,15]],"date-time":"2013-04-15T16:43:45Z","timestamp":1366044225000},"page":"1053-1057","source":"Crossref","is-referenced-by-count":10,"title":["Human papillomavirus was not detected by PCR using multiple consensus primer sets in esophageal adenocarcinomas in Chinese 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