{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T12:32:39Z","timestamp":1774701159298,"version":"3.50.1"},"reference-count":15,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2013,9,23]],"date-time":"2013-09-23T00:00:00Z","timestamp":1379894400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2014,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:label\/><jats:p>Respiratory viruses (RVs) are ubiquitous pathogens that represent a major cause of community\u2010acquired pneumonia and chronic pulmonary diseases exacerbations. However, their contribution to acute respiratory failure events requiring intensive care unit admission in the era of rapid multiplex molecular assay deserves further evaluation. This study investigated the burden of viral infections in non immunocompromised patients admitted to the intensive care unit for acute respiratory failure using a multiplex molecular assay. Patients were investigated for RVs using immunofluoresence testing and a commercial multiplex molecular assay, and for bacteria using conventional culture. Half the patients (34\/70, 49%) had a documented RVs infection. No other pathogen was found in 24 (71%) patients. Viral infection was detected more frequently in patients with obstructive respiratory diseases (64% vs. 29%; <jats:italic>P<\/jats:italic>\u2009=\u20090.0075). Multiplex molecular assay should be considered as an usefull diagnostic tool in patients admitted to the intensive care unit with acute respiratory failure, especially those with acute exacerbations of chronic obstructive pulmonary disease and asthma. <jats:bold><jats:italic>J. Med. Virol. 86:1198\u20131202, 2014<\/jats:italic>.<\/jats:bold> \u00a9 2013 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmv.23760","type":"journal-article","created":{"date-parts":[[2013,10,12]],"date-time":"2013-10-12T00:59:47Z","timestamp":1381539587000},"page":"1198-1202","source":"Crossref","is-referenced-by-count":18,"title":["Burden of respiratory viruses in patients with acute respiratory failure"],"prefix":"10.1002","volume":"86","author":[{"given":"David","family":"Schnell","sequence":"first","affiliation":[{"name":"Medical ICU AP\u2010HP, H\u00f4pital Saint\u2010Louis Paris France"},{"name":"Paris\u2010Diderot University, UFR de M\u00e9decine Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maud","family":"Gits\u2010Muselli","sequence":"additional","affiliation":[{"name":"Paris\u2010Diderot University, UFR de M\u00e9decine, Sorbone Paris Cit\u00e9, Microbiology laboratory, H\u00f4pital Saint\u2010Louis, APHP Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emmanuel","family":"Canet","sequence":"additional","affiliation":[{"name":"Medical ICU AP\u2010HP, H\u00f4pital Saint\u2010Louis Paris France"},{"name":"Paris\u2010Diderot University, UFR de M\u00e9decine Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Virginie","family":"Lemiale","sequence":"additional","affiliation":[{"name":"Medical ICU AP\u2010HP, H\u00f4pital Saint\u2010Louis Paris France"},{"name":"Paris\u2010Diderot University, UFR de M\u00e9decine Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beno\u00eet","family":"Schlemmer","sequence":"additional","affiliation":[{"name":"Medical ICU AP\u2010HP, H\u00f4pital Saint\u2010Louis Paris France"},{"name":"Paris\u2010Diderot University, UFR de M\u00e9decine Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fran\u00e7ois","family":"Simon","sequence":"additional","affiliation":[{"name":"Paris\u2010Diderot University, UFR de M\u00e9decine, Sorbone Paris Cit\u00e9, Microbiology laboratory, H\u00f4pital Saint\u2010Louis, APHP Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elie","family":"Azoulay","sequence":"additional","affiliation":[{"name":"Medical ICU AP\u2010HP, H\u00f4pital Saint\u2010Louis Paris France"},{"name":"Paris\u2010Diderot University, UFR de M\u00e9decine Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00e9r\u00f4me","family":"Legoff","sequence":"additional","affiliation":[{"name":"Paris\u2010Diderot University, UFR de M\u00e9decine, Sorbone Paris Cit\u00e9, Microbiology laboratory, H\u00f4pital Saint\u2010Louis, APHP Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,9,23]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0761-8425(08)71584-5"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.38.8.2824-2828.2000"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-005-2861-4"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(97)00003-X"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/cc5059"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.125.4.1343"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)15021-0"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.02094-10"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.43.1.455-457.2005"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.122.4.1264"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.39.8.2779-2783.2001"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.02294-07"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cir044"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1086\/338238"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.35.6.1579-1581.1997"}],"container-title":["Journal of Medical Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjmv.23760","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmv.23760","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T11:39:11Z","timestamp":1696333151000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmv.23760"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,9,23]]},"references-count":15,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2014,7]]}},"alternative-id":["10.1002\/jmv.23760"],"URL":"https:\/\/doi.org\/10.1002\/jmv.23760","archive":["Portico"],"relation":{},"ISSN":["0146-6615","1096-9071"],"issn-type":[{"value":"0146-6615","type":"print"},{"value":"1096-9071","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,9,23]]}}}