{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T18:19:13Z","timestamp":1788200353850,"version":"build-2803163510"},"reference-count":21,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2014,2,20]],"date-time":"2014-02-20T00:00:00Z","timestamp":1392854400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2014,6]]},"abstract":"<jats:sec>\n                    <jats:label\/>\n                    <jats:p>\n                      Tonsillar and adenoidal hypertrophy are prevalent otolaryngologic disorders in children, but their pathogenesis is largely unknown. The presence of human papillomavirus (HPV) and Epstein\u2013Barr virus (EBV) DNA in 146 tonsil and\/or adenoid tissue specimens from 104 Chinese children with tonsillar and\/or adenoidal hypertrophy were screened using flow\u2010through hybridization gene\u2010chip technology and real\u2010time fluorescence\u2010based quantitative PCR. Then, the relationships between the prevalence of the viruses and other clinical characteristics of tonsillar and\/or adenoidal hypertrophy were analyzed. No patient had HPV DNA. EBV DNA was detected in 19\/42 (45.2%) tonsil tissues and 72\/104 (69.2%) adenoid tissue specimens (\n                      <jats:italic>P\u2009<\/jats:italic>\n                      &lt;\u20090.05). EBV DNA was not related to the patients' age, gender, disease course, or nationality, but children positive for EBV were less likely to snore; 14\/15 (93.3%) patients who did not snore and 59\/89 (66.3%) patients who snored were EBV positive. EBV DNA, but not HPV DNA was detected in Chinese children with tonsillar and\/or adenoidal hypertrophy. Adenoid tissues might more susceptible than tonsil tissues to EBV infection. In addition, EBV infection did not aggravate snoring in patients with tonsillar and\/or adenoidal hypertrophy.\n                      <jats:bold>\n                        <jats:italic>J. Med. Virol. 86:963\u2013967, 2014<\/jats:italic>\n                        .\n                      <\/jats:bold>\n                      \u00a9 2014 Wiley Periodicals, Inc.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jmv.23894","type":"journal-article","created":{"date-parts":[[2014,2,20]],"date-time":"2014-02-20T23:41:18Z","timestamp":1392939678000},"page":"963-967","source":"Crossref","is-referenced-by-count":24,"title":["Prevalence of human papillomavirus and Epstein\u2013Barr virus DNA in Chinese children with tonsillar and\/or adenoidal hypertrophy"],"prefix":"10.1002","volume":"86","author":[{"given":"Xiao\u2010cheng","family":"Xue","sequence":"first","affiliation":[{"name":"Postgraduate Education College Ningxia Medical University Yinchuan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao\u2010ping","family":"Chen","sequence":"additional","affiliation":[{"name":"Shanghai Pudong New Area Gongli Hospital Shanghai 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