{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T02:20:25Z","timestamp":1744165225233},"reference-count":17,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2014,10,20]],"date-time":"2014-10-20T00:00:00Z","timestamp":1413763200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2015,3]]},"abstract":"<jats:sec><jats:label \/><jats:p>To investigate the distribution of high\u2010risk human papillomavirus (HPV) genotypes in infected women from Beijing, China, samples were obtained during routine gynecologic examinations and DNA was extracted from the samples, and PCR was performed to distinguish the 13 high\u2010risk HPV subtypes (16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, and 68). Samples were obtained from 1160 women (20\u201375 years old), and 470 cases of high\u2010risk HPV infection were diagnosed. HPV 52, HPV 16, HPV 58, HPV 51, and HPV 39 were the most common genotypes accounting for 22.8%, 22.3%, 20.0%, 14.3%, and 13.6% of cases, respectively. The highest infection rates were found in 20\u201330 year\u2010old patients (35.1%). HPV 16 infection was the highest in the 31\u201340 year\u2010old group, and HPV 52, HPV 58, and HPV 39 infections were highest in the 20\u201330 year\u2010old group. Some patients were infected with multiple high\u2010risk HPV subtypes. Of the 470 patients with positive HPV tests, 65.7% of women were infected with a single high\u2010risk HPV subtype, 23.2%, of women were infected with two high\u2010risk HPV subtypes, 7.7% were infected with three subtypes, and 3.4% of women were infected with more than three high\u2010risk HPV subtypes. In this study, HPV 16 and HPV 52 were the most common subtypes found in patients with cervical lesions. <jats:bold><jats:italic>J. Med. Virol. 87:504\u2013507, 2015<\/jats:italic>.<\/jats:bold> \u00a9 2014 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmv.24075","type":"journal-article","created":{"date-parts":[[2014,10,20]],"date-time":"2014-10-20T21:15:47Z","timestamp":1413839747000},"page":"504-507","source":"Crossref","is-referenced-by-count":17,"title":["Distribution of high\u2010risk human papillomavirus genotypes in HPV\u2010infected women in Beijing, China"],"prefix":"10.1002","volume":"87","author":[{"given":"Shuang","family":"Lu","sequence":"first","affiliation":[{"name":"Molecular Diagnostics Center, Clinical Laboratory China\u2010Japan Friendship Hospital Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao","family":"Cong","sequence":"additional","affiliation":[{"name":"Molecular Diagnostics Center, Clinical Laboratory China\u2010Japan Friendship Hospital Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology China\u2010Japan Friendship Hospital Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"FengXia","family":"Chang","sequence":"additional","affiliation":[{"name":"Clinical Laboratory 4th Qing Hai People's Hospital QingHai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liang","family":"Ma","sequence":"additional","affiliation":[{"name":"Molecular Diagnostics Center, Clinical Laboratory China\u2010Japan Friendship Hospital Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong Tong","family":"Cao","sequence":"additional","affiliation":[{"name":"Molecular Diagnostics Center, Clinical Laboratory China\u2010Japan Friendship Hospital Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,10,20]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1438.2007.00959.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/87.11.796"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1006\/gyno.1996.0028"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.24495"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9071(199910)59:2<232::AID-JMV18>3.0.CO;2-7"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-04-0812"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2008.07.077"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0215(19970207)70:4<408::AID-IJC6>3.0.CO;2-#"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.3802\/jgo.2009.20.1.1"},{"key":"e_1_2_6_11_1","first-page":"4171","article-title":"Genetic alterations accumulate during cervical tumorigenesis and indicate a common origin for multifocal lesions","volume":"57","author":"Larson AA","year":"1997","journal-title":"Cancer Res"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-10-0212"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006250-199203000-00002"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.cej.0000178079.29533.1e"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa021641"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/IGC.0b013e31827670fd"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2008.05.042"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.21327"}],"container-title":["Journal of Medical Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjmv.24075","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmv.24075","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T14:50:21Z","timestamp":1696603821000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmv.24075"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,10,20]]},"references-count":17,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2015,3]]}},"alternative-id":["10.1002\/jmv.24075"],"URL":"https:\/\/doi.org\/10.1002\/jmv.24075","archive":["Portico"],"relation":{},"ISSN":["0146-6615","1096-9071"],"issn-type":[{"value":"0146-6615","type":"print"},{"value":"1096-9071","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,10,20]]}}}