{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T15:22:23Z","timestamp":1782400943972,"version":"3.54.5"},"reference-count":36,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":195,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001323","name":"Poliomyelitis Research Foundation","doi-asserted-by":"publisher","award":["152\/06"],"award-info":[{"award-number":["152\/06"]}],"id":[{"id":"10.13039\/501100001323","id-type":"DOI","asserted-by":"publisher"}]},{"name":"National Health Laboratory Services Research Trust"},{"name":"University of the Free State Cluster Funding"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Med. Virol."],"published-print":{"date-parts":[[2015,5]]},"DOI":"10.1002\/jmv.24079","type":"journal-article","created":{"date-parts":[[2015,2,18]],"date-time":"2015-02-18T18:25:11Z","timestamp":1424283911000},"page":"717-724","source":"Crossref","is-referenced-by-count":11,"title":["Comparative analysis of the L, M, and S RNA segments of Crimean-Congo haemorrhagic fever virus isolates from southern Africa"],"prefix":"10.1002","volume":"87","author":[{"given":"Dominique","family":"Goedhals","sequence":"first","affiliation":[{"name":"Department of Medical Microbiology and Virology; National Health Laboratory Service\/University of the Free State; Bloemfontein South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phillip A.","family":"Bester","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology and Virology; National Health Laboratory Service\/University of the Free State; Bloemfontein South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janusz T.","family":"Paweska","sequence":"additional","affiliation":[{"name":"Center for Emerging and Zoonotic Pathogens; National Institute for Communicable Diseases; National Health Laboratory Service; Johannesburg South Africa"},{"name":"School of Pathology; Faculty of Health Sciences; University of the Witswatersrand; South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Swanepoel","sequence":"additional","affiliation":[{"name":"Zoonoses Research Unit; Department of Medical Virology; University of Pretoria; South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felicity J.","family":"Burt","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology and Virology; National Health Laboratory Service\/University of the Free State; Bloemfontein South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,2,18]]},"reference":[{"key":"10.1002\/jmv.24079-BIB0001|jmv24079-cit-0001","doi-asserted-by":"crossref","first-page":"6632","DOI":"10.1128\/JVI.02730-06","article-title":"Identification of a novel C-terminal cleavage of Crimean-Congo hemorrhagic fever virus PreGN that leads to generation of an NSM protein","volume":"81","author":"Altamura","year":"2007","journal-title":"J Virol"},{"key":"10.1002\/jmv.24079-BIB0002|jmv24079-cit-0002","doi-asserted-by":"crossref","first-page":"3389","DOI":"10.1093\/nar\/25.17.3389","article-title":"Gapped BLAST and PSI-BLAST: A new generation of protein database search programs","volume":"25","author":"Altschul","year":"1997","journal-title":"Nucleic Acids Res"},{"key":"10.1002\/jmv.24079-BIB0003|jmv24079-cit-0003","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1128\/JVI.78.3.1129-1138.2004","article-title":"Bunyamwera Bunyavirus RNA synthesis requires cooperation of =- and 5-terminal sequences","volume":"78","author":"Barr","year":"2004","journal-title":"J Virol"},{"key":"10.1002\/jmv.24079-BIB0004|jmv24079-cit-0004","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.antiviral.2013.07.006","article-title":"Crimean-Congo hemorrhagic fever: History, epidemiology, pathogenesis, clinical syndrome and genetic diversity","volume":"100","author":"Bente","year":"2013","journal-title":"Antiviral Res"},{"key":"10.1002\/jmv.24079-BIB0005|jmv24079-cit-0005","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1128\/JVI.01859-09","article-title":"Crimean-Congo hemorrhagic fever virus-encoded ovarian tumor protease activity is dispensable for virus RNA polymerase function","volume":"84","author":"Bergeron","year":"2010","journal-title":"J Virol"},{"key":"10.1002\/jmv.24079-BIB0006|jmv24079-cit-0006","doi-asserted-by":"crossref","first-page":"3621","DOI":"10.1128\/JVI.02496-10","article-title":"Structural analysis of a viral ovarian tumor domain protease from the Crimean-Congo hemorrhagic fever virus in complex with covalently bonded ubiquitin","volume":"85","author":"Capodagli","year":"2011","journal-title":"J Virol"},{"key":"10.1002\/jmv.24079-BIB0007|jmv24079-cit-0007","doi-asserted-by":"crossref","first-page":"10914","DOI":"10.1128\/JVI.01555-12","article-title":"Structure, function and evoluation of the Crimean-Congo hemorrhagic fever virus nucleocapsid protein","volume":"86","author":"Carter","year":"2012","journal-title":"J Virol"},{"key":"10.1002\/jmv.24079-BIB0008|jmv24079-cit-0008","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1099\/0022-1317-55-1-165","article-title":"Structural characteristics of nairoviruses (genus Nairovirus, Bunyaviridae)","volume":"55","author":"Clerx","year":"1981","journal-title":"J Gen Virol"},{"key":"10.1002\/jmv.24079-BIB0009|jmv24079-cit-0009","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/1743-422X-5-7","article-title":"The complete genome sequence of a Crimean-Congo hemorrhagic fever virus isolated from an endemic region in Kosovo","volume":"5","author":"Duh","year":"2008","journal-title":"Virol J"},{"key":"10.1002\/jmv.24079-BIB0010|jmv24079-cit-0010","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1016\/j.virol.2006.11.023","article-title":"N-linked glycosylation of Gn (but not Gc) is important for Crimean Congo hemorrhagic fever virus glycoprotein localization and transport","volume":"361","author":"Erickson","year":"2007","journal-title":"Virology"},{"key":"10.1002\/jmv.24079-BIB0011|jmv24079-cit-0011","doi-asserted-by":"crossref","first-page":"21678","DOI":"10.1074\/jbc.M110.216515","article-title":"Structural characterization of the Crimean-Congo hemorrhagic fever virus Gn tail provides insight into virus assembly","volume":"286","author":"Estrada","year":"2011","journal-title":"J Biol Chem"},{"key":"10.1002\/jmv.24079-BIB0012|jmv24079-cit-0012","doi-asserted-by":"crossref","first-page":"D211","DOI":"10.1093\/nar\/gkp985","article-title":"The Pfam protein families database","volume":"38","author":"Finn","year":"2010","journal-title":"Nucleic Acids Res"},{"key":"10.1002\/jmv.24079-BIB0013|jmv24079-cit-0013","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1016\/j.chom.2007.09.014","article-title":"Ovarian tumor domain-containing viral proteases evade ubiquitin- and ISG 15-dependent innate immune responses","volume":"2","author":"Frias-Staheli","year":"2007","journal-title":"Cell Host Microbe"},{"key":"10.1002\/jmv.24079-BIB0014|jmv24079-cit-0014","doi-asserted-by":"crossref","first-page":"1952","DOI":"10.1017\/S0950268814000818","article-title":"Next-generation sequencing of southern African Crimean-Congo haemorrhagic fever virus isolates reveals a high frequency of M segment reassortment","volume":"142","author":"Goedhals","year":"2014","journal-title":"Epidemiol Infect"},{"key":"10.1002\/jmv.24079-BIB0015|jmv24079-cit-0015","doi-asserted-by":"crossref","first-page":"5046","DOI":"10.1073\/pnas.1200808109","article-title":"Crimean-Congo hemorrhagic fever virus nucleoprotein reveals endonuclease activity in bunyaviruses","volume":"109","author":"Guo","year":"2012","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1002\/jmv.24079-BIB0016|jmv24079-cit-0016","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.virol.2003.09.042","article-title":"Crimean-Congo hemorrhagic fever virus genome L RNA segment and encoded protein","volume":"321","author":"Honig","year":"2004","journal-title":"Virology"},{"key":"10.1002\/jmv.24079-BIB0017|jmv24079-cit-0017","doi-asserted-by":"crossref","first-page":"6719","DOI":"10.1128\/JVI.75.14.6719-6728.2001","article-title":"Essential role of cyclization sequences in flavivirus RNA replication","volume":"75","author":"Khromykh","year":"2001","journal-title":"J Virol"},{"key":"10.1002\/jmv.24079-BIB0018|jmv24079-cit-0018","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.virol.2003.09.046","article-title":"Sequence determination of the Crimean-Congo hemorrhagic fever virus L segment","volume":"321","author":"Kinsella","year":"2004","journal-title":"Virology"},{"key":"10.1002\/jmv.24079-BIB0019|jmv24079-cit-0019","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1006\/jmbi.2000.4315","article-title":"Predicting transmembrane protein topology with a hidden Markov model: Application to complete genomes","volume":"305","author":"Krogh","year":"2001","journal-title":"J Mol Biol"},{"key":"10.1002\/jmv.24079-BIB0020|jmv24079-cit-0020","doi-asserted-by":"crossref","first-page":"2947","DOI":"10.1093\/bioinformatics\/btm404","article-title":"Clustal W and Clustal X version 2.0","volume":"23","author":"Larkin","year":"2007","journal-title":"Bioinformatics"},{"key":"10.1002\/jmv.24079-BIB0021|jmv24079-cit-0021","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1007\/s00705-013-1940-z","article-title":"The molecular biology of nairoviruses, an emerging group of tick-borne arboviruses","volume":"159","author":"Lasecka","year":"2013","journal-title":"Arch Virol"},{"key":"10.1002\/jmv.24079-BIB0022|jmv24079-cit-0022","doi-asserted-by":"crossref","first-page":"19504","DOI":"10.2807\/ese.15.10.19504-en","article-title":"Crimean-Congo haemorrhagic fever in Europe: Current situation calls for preparedness","volume":"15","author":"Maltezou","year":"2010","journal-title":"Euro Surveill"},{"key":"10.1002\/jmv.24079-BIB0023|jmv24079-cit-0023","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1016\/0042-6822(92)90898-Y","article-title":"Dugbe Nairovirus M RNA: Nucleotide sequence and coding strategy","volume":"190","author":"Marriott","year":"1992","journal-title":"Virology"},{"key":"10.1002\/jmv.24079-BIB0024|jmv24079-cit-0024","volume-title":"ICTVdB - The universal virus database, version 4","author":"Nichol","year":"2006"},{"key":"10.1002\/jmv.24079-BIB0025|jmv24079-cit-0025","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.virusres.2009.11.009","article-title":"The complete genome analysis of Crimean-Congo hemorrhagic fever virus isolated in Turkey","volume":"147","author":"Ozdarendeli","year":"2010","journal-title":"Virus Res"},{"key":"10.1002\/jmv.24079-BIB0026|jmv24079-cit-0026","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1038\/nmeth.1701","article-title":"SignalP 4.0: Discriminating signal peptides from transmembrane regions","volume":"8","author":"Petersen","year":"2011","journal-title":"Nat Methods"},{"key":"10.1002\/jmv.24079-BIB0027|jmv24079-cit-0027","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1128\/JVI.80.1.514-525.2006","article-title":"Crimean-Congo hemorrhagic fever virus glycoprotein precursor is cleaved by furin-like and SKI-1 proteases to generate a novel 38 kilodalton glycoprotein","volume":"80","author":"Sanchez","year":"2006","journal-title":"J Virol"},{"key":"10.1002\/jmv.24079-BIB0028|jmv24079-cit-0028","doi-asserted-by":"crossref","first-page":"1478","DOI":"10.1038\/emboj.2013.79","article-title":"Precision mapping of the human O-GalNAc glycoproteome through SimpleCell technology","volume":"32","author":"Steentoft","year":"2013","journal-title":"EMBO J"},{"key":"10.1002\/jmv.24079-BIB0029|jmv24079-cit-0029","doi-asserted-by":"crossref","first-page":"2731","DOI":"10.1093\/molbev\/msr121","article-title":"MEGA5: Molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods","volume":"28","author":"Tamura","year":"2011","journal-title":"Mol Biol Evol"},{"key":"10.1002\/jmv.24079-BIB0030|jmv24079-cit-0030","doi-asserted-by":"crossref","first-page":"8640","DOI":"10.1128\/JVI.77.16.8640-8649.2003","article-title":"Crimean-Congo hemorrhagic fever virus glycoprotein proteolytic processing by subtilase SKI-1","volume":"77","author":"Vincent","year":"2003","journal-title":"J Virol"},{"key":"10.1002\/jmv.24079-BIB0031|jmv24079-cit-0031","doi-asserted-by":"crossref","first-page":"4690","DOI":"10.1128\/JVI.02358-08","article-title":"Relaxed selection and the evolution of RNA virus mucin-like pathogenicity factors","volume":"83","author":"Wertheim","year":"2009","journal-title":"J Virol"},{"key":"10.1002\/jmv.24079-BIB0032|jmv24079-cit-0032","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.meegid.2012.10.005","article-title":"Genetic characterization and molecular clock analyses of the Crimean-Congo hemorrhagic fever virus from human and ticks in India, 2010-2011","volume":"14","author":"Yadav","year":"2013","journal-title":"Infect Genet Evol"},{"key":"10.1002\/jmv.24079-BIB0033|jmv24079-cit-0033","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1038\/78645","article-title":"Identification of the Ebola virus glycoprotein as the main viral determinant of vascular cell cytotoxicity and injury","volume":"6","author":"Yang","year":"2000","journal-title":"Nat Med"},{"key":"10.1002\/jmv.24079-BIB0034|jmv24079-cit-0034","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1093\/bioinformatics\/17.9.847","article-title":"InterProScan-An integration platform for the signature-recognition methods in InterPro","volume":"17","author":"Zdobnov","year":"2001","journal-title":"Bioinformatics"},{"key":"10.1002\/jmv.24079-BIB0035|jmv24079-cit-0035","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1093\/glycob\/cwh106","article-title":"Tracking global patterns of N-linked glycosylation site variation in highly variable viral glycoproteins: HIV, SIV, and HCV envelopes and influenza hemagglutinin","volume":"14","author":"Zhang","year":"2004","journal-title":"Glycobiology"},{"key":"10.1002\/jmv.24079-BIB0036|jmv24079-cit-0036","doi-asserted-by":"crossref","first-page":"3406","DOI":"10.1093\/nar\/gkg595","article-title":"Mfold web server for nucleic acid folding and hybridization prediction","volume":"31","author":"Zuker","year":"2003","journal-title":"Nucleic Acids Res"}],"container-title":["Journal of Medical Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjmv.24079","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1002\/jmv.24079\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,30]],"date-time":"2022-04-30T03:42:50Z","timestamp":1651290170000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmv.24079"}},"subtitle":["Comparative Analysis of the CCHFV Genome"],"short-title":[],"issued":{"date-parts":[[2015,2,18]]},"references-count":36,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2015,5]]}},"URL":"https:\/\/doi.org\/10.1002\/jmv.24079","relation":{},"ISSN":["0146-6615"],"issn-type":[{"value":"0146-6615","type":"print"}],"subject":[],"published":{"date-parts":[[2015,2,18]]}}}