{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T03:43:33Z","timestamp":1776051813235,"version":"3.50.1"},"reference-count":29,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2015,10,29]],"date-time":"2015-10-29T00:00:00Z","timestamp":1446076800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2016,1]]},"abstract":"<jats:sec><jats:label\/><jats:p>Human rhinovirus (RV) is a common cause of acute respiratory infection (ARI) in children. We aimed to characterize the clinical and demographic features associated with different RV species detected in children attending hospital with ARI, from low\u2010income families in North\u2010east Brazil. Nasopharyngeal aspirates were collected from 630 children &lt;5 years with ARI. Clinical diagnosis and disease severity were also recorded. Samples were analyzed by multiplex PCR for 18 viral and atypical bacterial pathogens; RV positive samples underwent partial sequencing to determine species and type. RV was the fourth commonest pathogen accounting for 18.7% of pathogens detected. RV was commonly detected in children with bronchiolitis, pneumonia, and asthma\/episodic viral wheeze (EVW). Species and type were assigned in 112 cases (73% RV\u2010A; 27% RV\u2010C; 0% RV\u2010B). Generally, there were no differences in clinical or demographic characteristics between those infected with RV\u2010A and RV\u2010C. However, in children with asthma\/EVW, RV\u2010C was detected relatively more frequently than RV\u2010A (23% vs. 5%; <jats:italic>P<\/jats:italic>\u2009=\u20090.04). Our findings highlight RV as a potentially important pathogen in this setting. Generally, clinical and demographic features were similar in children in whom RV\u2010A and C species were detected. However, RV\u2010C was more frequently found in children with asthma\/EVW than RV\u2010A. <jats:bold><jats:italic>J. Med. Virol. 88:58\u201363, 2016<\/jats:italic>.<\/jats:bold> \u00a9 2015 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmv.24300","type":"journal-article","created":{"date-parts":[[2015,6,22]],"date-time":"2015-06-22T22:42:45Z","timestamp":1435012965000},"page":"58-63","source":"Crossref","is-referenced-by-count":25,"title":["Rhinovirus\u2010C detection in children presenting with acute respiratory infection to hospital in Brazil"],"prefix":"10.1002","volume":"88","author":[{"given":"David W.","family":"Fawkner\u2010Corbett","sequence":"first","affiliation":[{"name":"Institute of Child Health Alder Hey Children's Hospital Liverpool United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siew Kim","family":"Khoo","sequence":"additional","affiliation":[{"name":"School of Paediatrics and Child Health University of Western Australia Perth Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carminha 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