{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T01:31:19Z","timestamp":1782437479776,"version":"3.54.5"},"reference-count":29,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2015,11,19]],"date-time":"2015-11-19T00:00:00Z","timestamp":1447891200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["26460743, 25461509"],"award-info":[{"award-number":["26460743, 25461509"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2016,6]]},"abstract":"<jats:sec><jats:label\/><jats:p>This cross\u2010sectional study investigated the prevalence, genotypes, and risk factors for human papillomavirus (HPV) infection in Hanoi, Vietnam. The study included 192 males (mean age, 32.9 years) with symptoms related to sexually transmitted infections (STI). Urinary, penile, and urethral samples were collected in April and May, 2014. HPV DNA was detected with PCR, performed with modified and\/or original GP5<jats:sup>+<\/jats:sup>\/GP6<jats:sup>+<\/jats:sup> primers. HPV genotypes were determined with a gene array assay. <jats:italic>Neisseria gonorrhoeae<\/jats:italic> (NG) and <jats:italic>Chlamydia trachomatis<\/jats:italic> (CT) DNA were detected with loop\u2010mediated isothermal amplification. HPV DNA, NG, and CT were detected in 48 (25.0%), 23 (12.0%), and 41 (21.4%) patients, respectively. HPV DNA appeared in penile samples (21.0%, 39\/186) more frequently than in urinary (3.1%, 6\/191, <jats:italic>P\u2009<\/jats:italic>&lt;\u20090.001) and urethral (9.4%, 18\/192, <jats:italic>P\u2009<\/jats:italic>=\u20090.002) samples. Among patients with HPV, genotype prevalence was: HPV81 (22.9%), \u2009HPV52 (18.8%), HPV18 (16.7%), and HPV16 (6.3%). Multiple\u2010type and high risk\u2010type HPV infections were determined in 33.3% and 64.6%, respectively. Multivariate analysis showed a significant association of HPV infection in urethra with younger sexual debut age. HPV52 was the most prevalent high\u2010risk HPV genotype, whereas HPV16 was less common in the male Vietnamese patients with STI\u2010related symptoms. Younger sexual\u2010debut age was a risk factor for HPV infection in urethra. <jats:bold><jats:italic>J. Med. 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