{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T09:43:24Z","timestamp":1790934204389,"version":"4.1.0"},"reference-count":51,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2015,12,14]],"date-time":"2015-12-14T00:00:00Z","timestamp":1450051200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Agriculture and Food Research Initiative Competitive","award":["2011-68003-30395"],"award-info":[{"award-number":["2011-68003-30395"]}]},{"name":"NoroCORE Graduate Research Fellowship"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2016,6]]},"abstract":"<jats:sec><jats:label\/><jats:p>Noroviruses are an important cause of gastroenteritis, which can be severe at the extremes of ages. Data documenting the endemic burden of norovirus among children and elderly adults are lacking. Stool specimens submitted for clinical testing were collected from elderly (\u226565 years) adults and children (&lt;18 years) with acute vomiting and\/or diarrhea seeking care at several metropolitan Atlanta adult and pediatric hospitals from January 2013\u2013June 2013. Specimens were tested for norovirus with real\u2010time RT\u2010PCR and sequenced if norovirus was detected. Corresponding clinical and demographic data were abstracted from retrospective chart review. Norovirus was detected in 11% (11\/104) of elderly specimens and 11% (67\/628) of pediatric, with GII.4 Sydney_2012 detected in 64% (7\/11) of elderly norovirus\u2010positive and 11% (8\/67) of pediatric specimens, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001. In comparison to hospitalized children, hospitalized elderly with norovirus were more commonly admitted to the intensive care unit (ICU) (36% vs. 7%, <jats:italic>P<\/jats:italic>\u2009=\u20090.02). Norovirus in the elderly can be associated with severe illness requiring ICU admissions. The pediatric group demonstrated greater variability in genotype distribution. Ongoing surveillance of norovirus genotypes is crucial for norovirus vaccine development in understanding circulating and emerging genotypes. <jats:italic><jats:bold>J. Med. Virol. 88:961\u2013970, 2016<\/jats:bold><\/jats:italic>. \u00a9 2015 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmv.24436","type":"journal-article","created":{"date-parts":[[2015,11,24]],"date-time":"2015-11-24T20:02:32Z","timestamp":1448395352000},"page":"961-970","source":"Crossref","is-referenced-by-count":12,"title":["Molecular epidemiology of norovirus in children and the elderly in Atlanta, Georgia, United States"],"prefix":"10.1002","volume":"88","author":[{"given":"Jumi","family":"Yi","sequence":"first","affiliation":[{"name":"Department of Pediatrics Emory University School of Medicine Atlanta Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelly","family":"Wahl","sequence":"additional","affiliation":[{"name":"Hubert Department of Global Health Rollins School of Public Health Emory University Atlanta Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bethany 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