{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,31]],"date-time":"2024-08-31T19:49:38Z","timestamp":1725133778698},"reference-count":30,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,7,20]],"date-time":"2016-07-20T00:00:00Z","timestamp":1468972800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Merck ClinicalTrials.gov","award":["NCT00932009"],"award-info":[{"award-number":["NCT00932009"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2017,2]]},"abstract":"<jats:sec><jats:label \/><jats:p>The objective of the study was to assess risk factors for Human Papillomavirus (HPV) among men in Tanzania, both overall and in relation to HIV status. In a cross\u2010sectional study conducted among 1,813 men in Tanzania, penile swabs were tested for HPV using Hybrid Capture 2 (HC2). Study participants were offered HIV testing. Risk factors for HPV (HC2 high\u2010risk and\/or low\u2010risk positivity) were assessed using logistic regression with adjustment for age, lifetime number of sexual partners, and HIV status. Altogether, 372 men (20.5%) were HPV\u2010positive. Among men tested for HIV (n\u2009=\u20091,483), the HIV prevalence was 9.4%. The odds ratio (OR) of HPV increased with increasing age. HIV\u2010positivity was associated with an increased odds ratio of HPV (OR\u2009=\u20091.91; 95%CI: 1.30\u20132.82), whereas the odds of HPV tended to be lower in circumcised men than in uncircumcised men (OR\u2009=\u20090.77; 95%CI: 0.54\u20131.09). When stratifying by HIV status, we found lower odds of HPV in overweight HIV\u2010positive men (BMI\u2009&gt;\u200925) than in normal weight HIV\u2010positive men (OR\u2009=\u20090.25; 95%CI: 0.08\u20130.78). This did not apply to HIV\u2010negative men. Circumcision tended to decrease the odds of HPV both in HIV\u2010positive men and in HIV\u2010negative men, although not being statistically significant. In conclusion, HIV is a strong risk factor for HPV among men in Tanzania. Additionally, in HIV\u2010positive men a high BMI seems to be associated with a lower risk of HPV. Finally, we observed a tendency toward a lower risk of HPV both among HIV\u2010positive and HIV\u2010negative circumcised men compared to their uncircumcised counterparts. <jats:bold><jats:italic>J. Med. 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