{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T02:15:15Z","timestamp":1740104115947,"version":"3.37.3"},"reference-count":15,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2017,2,27]],"date-time":"2017-02-27T00:00:00Z","timestamp":1488153600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["124309"],"award-info":[{"award-number":["124309"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:sec><jats:label\/><jats:p>We compared pairs of self\u2010 and investigator\u2010collected mid\u2010turbinate nasal swabs to detect and quantify influenza viral loads. We used RNase P, which reflects presence of human cells to determine adequate sample collection. Sixteen pairs of influenza\u2010positive swabs and 25 pairs of influenza\u2010negative swabs were included in this study. The median influenza A viral loads for self\u2010 and investigator\u2010collected swabs were 1.68 and 1.67 log<jats:sub>10<\/jats:sub> copies\/mL, respectively (<jats:italic>P<\/jats:italic>\u2009=\u20090.96). RNase P loads were also similar between self\u2010 and investigator\u2010collected swabs (<jats:italic>P<\/jats:italic>\u2009=\u20090.51). Self\u2010collected mid\u2010turbinate nasal swabs yield comparable viral loads to investigator\u2010collected swabs, and therefore might be considered for research and clinical management.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmv.24753","type":"journal-article","created":{"date-parts":[[2016,12,12]],"date-time":"2016-12-12T12:37:46Z","timestamp":1481546266000},"page":"1295-1299","source":"Crossref","is-referenced-by-count":6,"title":["Detecting and quantifying influenza virus with self\u2010 versus investigator\u2010collected mid\u2010turbinate nasal swabs"],"prefix":"10.1002","volume":"89","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0873-6317","authenticated-orcid":false,"given":"Andrea","family":"Granados","sequence":"first","affiliation":[{"name":"Public Health Ontario Toronto Ontario Canada"},{"name":"Department of Laboratory Medicine and Pathobiology University of Toronto Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan","family":"Quach","sequence":"additional","affiliation":[{"name":"Public Health Ontario Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allison","family":"McGeer","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine and Pathobiology University of Toronto Toronto Ontario Canada"},{"name":"Sinai Health System Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan B.","family":"Gubbay","sequence":"additional","affiliation":[{"name":"Public Health Ontario Toronto Ontario Canada"},{"name":"Department of Laboratory Medicine and Pathobiology University of Toronto Toronto Ontario Canada"},{"name":"The Hospital for Sick Children Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey C.","family":"Kwong","sequence":"additional","affiliation":[{"name":"Public Health Ontario Toronto Ontario Canada"},{"name":"Dalla Lana School of Public Health University of Toronto Toronto Ontario Canada"},{"name":"Institute for Clinical Evaluative Sciences Toronto Ontario Canada"},{"name":"Department of Family and Community Medicine University of Toronto Toronto Ontario Canada"},{"name":"University Health Network Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,2,27]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2011.07.005"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0048508"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/jpids\/pit039"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.02235-09"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00327-11"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2015.05.001"},{"key":"e_1_2_7_8_1","first-page":"1","article-title":"Pilot study of participant\u2010collected nasal swabs for acute respiratory infections in a low\u2010income, urban population","volume":"8","author":"Vargas C","year":"2016","journal-title":"Clin Epidemiol"},{"key":"e_1_2_7_9_1","first-page":"534","article-title":"Randomized evaluation of live attenuated versus inactivated influenza vaccines in schools (RELATIVES) pilot study: A cluster randomized trial","volume":"33","author":"Kwong J","year":"2015","journal-title":"Vaccine"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2015.07.044"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.23375"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01739-07"},{"key":"e_1_2_7_13_1","first-page":"384","article-title":"Use of an improved quantitative polymerase chain reaction assay to determine differences in human rhinovirus viral loads in different populations","volume":"74","author":"Granados A","year":"2012","journal-title":"DMID"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep14268"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/irv.12309"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.02055-05"}],"container-title":["Journal of Medical Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjmv.24753","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmv.24753","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,9]],"date-time":"2023-09-09T20:02:04Z","timestamp":1694289724000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmv.24753"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2,27]]},"references-count":15,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2017,7]]}},"alternative-id":["10.1002\/jmv.24753"],"URL":"https:\/\/doi.org\/10.1002\/jmv.24753","archive":["Portico"],"relation":{},"ISSN":["0146-6615","1096-9071"],"issn-type":[{"type":"print","value":"0146-6615"},{"type":"electronic","value":"1096-9071"}],"subject":[],"published":{"date-parts":[[2017,2,27]]}}}