{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T13:27:20Z","timestamp":1790342840388,"version":"4.1.0"},"reference-count":27,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2017,3,3]],"date-time":"2017-03-03T00:00:00Z","timestamp":1488499200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2017,8]]},"abstract":"<jats:sec><jats:label\/><jats:p>Dengue is a mosquito\u2010borne disease of public health importance. It is caused by four serotypes of Dengue virus (i.e, DENV\u20101, \u20102, \u20103, and \u20104). As a result of practices that are conducive for mosquito breading, its vector is widespread in Nigeria and this could result to possible DENV outbreaks in Nigeria and beyond. This study aimed to assess the recency of DENV infection as well as occurrence of DENV and Malaria co\u2010infections within Ilorin, Nigeria. Blood samples were obtained from 176 febrile subjects and analyzed using Enzyme Linked Immunosorbent Assay (ELISA) for the presence of DENV antibodies. Malaria infection was detected using a rapid diagnostic test kit for malaria parasites. Malaria and DENV (IgM positive) co\u2010infected samples were further subjected to RT\u2010qPCR analysis. A seroprevalence of 46.0% was recorded for anti\u2010DENV IgM antibodies and 2.84% for concurrent Dengue and malaria infections. Out of 95 IgM negative samples, 48 were found to be positive for DENV IgG antibodies. Eleven (6.25%) samples were confirmed DENV positive following RT\u2010qPCR. The CT values of the amplicons were between 19.0 and 20.0. DENV serotype 2 dominated the study, while serotype 3 and 4 were equally distributed. Based on the high seroprevalence of DENV obtained in this study, there is a high possibility of experiencing Dengue virus outbreak in Ilorin, Nigeria, not neglecting the fast geographical spread of the vector. Therefore, surveillance and intensive vector control program should be instituted.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmv.24788","type":"journal-article","created":{"date-parts":[[2017,2,15]],"date-time":"2017-02-15T11:32:44Z","timestamp":1487158364000},"page":"1347-1353","source":"Crossref","is-referenced-by-count":31,"title":["Dengue virus and malaria concurrent infection among febrile subjects within Ilorin metropolis, Nigeria"],"prefix":"10.1002","volume":"89","author":[{"given":"Olatunji Matthew","family":"Kolawole","sequence":"first","affiliation":[{"name":"Infectious Diseases and Environmental Health Research Group Department of Microbiology Faculty of Life Sciences University of Ilorin Ilorin Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adebimpe Adetola","family":"Seriki","sequence":"additional","affiliation":[{"name":"Infectious Diseases and Environmental Health Research Group Department of Microbiology Faculty of Life Sciences University of Ilorin Ilorin Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1779-9571","authenticated-orcid":false,"given":"Ahmad Adebayo","family":"Irekeola","sequence":"additional","affiliation":[{"name":"Infectious Diseases and Environmental Health Research Group Department of Microbiology Faculty of Life Sciences University of Ilorin Ilorin Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kizito Eneye","family":"Bello","sequence":"additional","affiliation":[{"name":"Infectious Diseases and Environmental Health Research Group Department of Microbiology Faculty of Life Sciences University of Ilorin Ilorin Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0848-5917","authenticated-orcid":false,"given":"Oluwapelumi Olufemi","family":"Adeyemi","sequence":"additional","affiliation":[{"name":"School of Molecular and Cellular Biology Faculty of Biological Sciences University of Leeds Leeds United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,3,3]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"World Health Organization (WHO).2012. 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Population distribution by Sex State LGA & Senatorial district: 2006 census population distribution by LGA Kwara state. [cited 2016 Mar 1] Available from:http:\/\/www.population.go.v.ng\/images\/vol%2003%20table%20dsx%20lgapop%20by%20sdistrict\u2010pdf.pdf."},{"key":"e_1_2_9_14_1","first-page":"594","article-title":"The prevalence of Dengue virus in brunei darussalam during january\u2014november 2010","volume":"44","author":"Rahman ZH","year":"2013","journal-title":"Southeast Asian J Trop Med Public Health"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/jmedent\/27.5.892"},{"key":"e_1_2_9_16_1","first-page":"245","volume-title":"The Arboviruses: Epidemiology and Ecology","author":"Reiter P.","year":"1988"},{"key":"e_1_2_9_17_1","doi-asserted-by":"crossref","first-page":"262","DOI":"10.4103\/0972-9062.213508","article-title":"Manifestation and outcome of concurrent malaria and Dengue infection","volume":"49","author":"Mohapatra MK","year":"2012","journal-title":"J Vector Borne Dis"},{"key":"e_1_2_9_18_1","first-page":"560","article-title":"Sero\u2010prevalence of Dengue type\u20103 virus among patients with febrile illnesses attending a tertiary hospital in Maiduguri, Nigeria","volume":"5","author":"Idris AN","year":"2013","journal-title":"Int J Med Med Sci"},{"key":"e_1_2_9_19_1","doi-asserted-by":"crossref","first-page":"21","DOI":"10.4314\/ajid.v10i1.4","article-title":"Incidence of Dengue virus in febrile episodes in Ile\u2010Ife, Nigeria","volume":"10","author":"Adesina OA","year":"2016","journal-title":"Afri J Infect Dis"},{"key":"e_1_2_9_20_1","first-page":"1255","article-title":"Seroprevalence of IgM antibodies to Dengue fever virus among patients presenting with symptoms of fever in some hospitals in kaduna state, Nigeria","volume":"5","author":"Bello OA","year":"2016","journal-title":"Int J Sci Res"},{"key":"e_1_2_9_21_1","first-page":"28","article-title":"The effect of climate on Dengue virus infection in Nigeria","volume":"4","author":"Baba MM","year":"2011","journal-title":"N Y Sci J"},{"key":"e_1_2_9_22_1","first-page":"129","article-title":"Dengue virus infections in patients suspected of malaria\/typhoid in Nigeria","volume":"5","author":"Baba MM","year":"2009","journal-title":"J Am Sci"},{"key":"e_1_2_9_23_1","first-page":"71","article-title":"Serological evidence of acute Dengue virus infection among febrile patients attending plateau state specialist hospital jos, Nigeria","volume":"2","author":"Dawurung JS","year":"2010","journal-title":"Rep Opinion"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.11604\/pamj.2013.16.73.2891"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2875-3-6"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.9734\/BMRJ\/2015\/15588"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0003416"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.3855\/jidc.2411"}],"container-title":["Journal of Medical Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjmv.24788","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmv.24788","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,22]],"date-time":"2024-06-22T13:50:23Z","timestamp":1719064223000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmv.24788"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3,3]]},"references-count":27,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2017,8]]}},"alternative-id":["10.1002\/jmv.24788"],"URL":"https:\/\/doi.org\/10.1002\/jmv.24788","archive":["Portico"],"relation":{},"ISSN":["0146-6615","1096-9071"],"issn-type":[{"value":"0146-6615","type":"print"},{"value":"1096-9071","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,3,3]]}}}