{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T22:33:29Z","timestamp":1778106809990,"version":"3.51.4"},"reference-count":31,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2017,4,26]],"date-time":"2017-04-26T00:00:00Z","timestamp":1493164800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003196","name":"Ministero della Salute","doi-asserted-by":"publisher","award":["RC 22 \/2014"],"award-info":[{"award-number":["RC 22 \/2014"]}],"id":[{"id":"10.13039\/501100003196","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:sec><jats:label\/><jats:p><jats:italic>Chlamydia trachomatis<\/jats:italic> and HPV coinfections in the male population are often a disregarded issue. We performed a study to evaluate the prevalence of such infections in heterosexual HIV negative men from a Northern Italy multi\u2010ethnic area at high prevalence for cervical malignancies. Urethral swabs (US) or first\u2010voided urine were evaluated retrospectively from 1317 patients attending Sexually Transmitted Infections (STI) clinic and from 3388 outpatients attending private clinics. Informations about participants\u2019 demographic characteristics and attributes of <jats:italic>C. trachomatis<\/jats:italic>, including chronic infection, and HPV genotypes testing, were collected. Exact Fisher test, bivariate, and multivariate logistic regressions were carried out. The prevalence of <jats:italic>C. trachomatis<\/jats:italic> was 1.7% in the outpatients and 16.9% in the STI group (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.0001) in which the highest frequency was observed in men of age \u226425 years. Among patients with <jats:italic>C. trachomatis<\/jats:italic>, asymptomatic HPV co\u2010infection was detected in 33% of men from the STI clinic and in 2% of the outpatients. Out of all coinfections, 56% were due to single HPV, with a prevalence of 73% in young STI men. The distribution of HPV genotypes confirmed the increased circulation of LR\u2010HPV42, HR\u2010HPV51, HR\u2010HPV52 and prHR\u2010HPV82, and the decreasing of HR\u2010HPV16. African nationalities and leucorrhea were significantly associated risk factors, while the regular condom use offered an effective protection. This study highlights the high prevalence of <jats:italic>C. trachomatis<\/jats:italic> and HPV asymptomatic co\u2010infection in young HIV negative men attending the STI clinic, representing a reservoir of new HPV genotypes with potential oncogenic risk.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmv.24811","type":"journal-article","created":{"date-parts":[[2017,3,19]],"date-time":"2017-03-19T05:56:45Z","timestamp":1489903005000},"page":"1654-1661","source":"Crossref","is-referenced-by-count":14,"title":["<i>Chlamydia trachomatis<\/i> and HPV co\u2010infections in HIV negative men from a multi\u2010ethnic area of Northern Italy at high prevalence of cervical malignancies"],"prefix":"10.1002","volume":"89","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6310-3320","authenticated-orcid":false,"given":"Manola","family":"Comar","sequence":"first","affiliation":[{"name":"Institute for Maternal and Child Health\u2014IRCCS \u201cBurlo Garofolo\u201d Trieste Italy"},{"name":"University of Trieste Trieste Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7774-548X","authenticated-orcid":false,"given":"Lorenzo","family":"Monasta","sequence":"additional","affiliation":[{"name":"Institute for Maternal and Child Health\u2014IRCCS \u201cBurlo Garofolo\u201d Trieste Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silva","family":"Seraceni","sequence":"additional","affiliation":[{"name":"Institute for Maternal and Child Health\u2014IRCCS \u201cBurlo Garofolo\u201d Trieste Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia","family":"Colli","sequence":"additional","affiliation":[{"name":"MST Centre ASUITS Trieste Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Viviana","family":"Luska","sequence":"additional","affiliation":[{"name":"Institute for Maternal and Child Health\u2014IRCCS \u201cBurlo Garofolo\u201d Trieste Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara","family":"Morassut","sequence":"additional","affiliation":[{"name":"Institute for Maternal and Child Health\u2014IRCCS \u201cBurlo Garofolo\u201d Trieste Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Libera","family":"Clemente","sequence":"additional","affiliation":[{"name":"Laboratory of Clinical Chemistry and Microbiological Analysis AAS2 \u201cBassa Friulana\u2014Sontina\u201d\u2014S. Polo General Hospital Monfalcone (GO) Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marina","family":"Drabeni","sequence":"additional","affiliation":[{"name":"Dermatology Center MST\/AIDS AAS2 \u201cBassa Friulana\u2014Isontina\u201d Gorizia Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gianmichele","family":"Moise","sequence":"additional","affiliation":[{"name":"Dermatology Center MST\/AIDS AAS2 \u201cBassa Friulana\u2014Isontina\u201d Gorizia Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Fontana","sequence":"additional","affiliation":[{"name":"Laboratory of Clinical Chemistry and Microbiological Analysis AAS2 \u201cBassa Friulana\u2014Sontina\u201d\u2014S. Polo General Hospital Monfalcone (GO) Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara","family":"Suligoi","sequence":"additional","affiliation":[{"name":"AIDS Operative Center\u2010ISS Roma Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,4,26]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/QCO.0000000000000235"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.5301\/uro.5000101"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-14663-3_2"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-015-1043-4"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0115753"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/183167"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2014.00534"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M110.137885"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/OLQ.0b013e318289c186"},{"key":"e_1_2_6_11_1","first-page":"4153","article-title":"Analysis of persistence of human papillomavirus infection in men evaluated by sampling multiple genital sites","volume":"19","author":"Capra G","year":"2015","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/det453"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jiac.2014.08.033"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-013-3122-3"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11033-013-2927-2"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000003077"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.24041"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.02105-12"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1186\/1750-9378-9-30"},{"key":"e_1_2_6_20_1","first-page":"333","article-title":"Background review for the \u201c2015 European guideline on the management of Chlamydia trachomatis infections","author":"Lanjouw E","year":"2015","journal-title":"Int J STD AIDS"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-011-1358-z"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-12-1003"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.000245"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/5584_2015_5015"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1086\/521629"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-2042.2010.02521.x"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1677-5538.IBJU.2014.02.16"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2010.11.047"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.5468\/ogs.2015.58.1.40"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2012.06.045"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910490304"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0151851"}],"container-title":["Journal of Medical Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjmv.24811","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmv.24811","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T23:32:01Z","timestamp":1696375921000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmv.24811"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4,26]]},"references-count":31,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2017,9]]}},"alternative-id":["10.1002\/jmv.24811"],"URL":"https:\/\/doi.org\/10.1002\/jmv.24811","archive":["Portico"],"relation":{},"ISSN":["0146-6615","1096-9071"],"issn-type":[{"value":"0146-6615","type":"print"},{"value":"1096-9071","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,4,26]]}}}