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From August 2010 to April 2011, 309 outpatients were recruited at the Luang Prabang Provincial Hospital covering highland Lao communities. Nasopharyngeal swabs were screened for the presence of 13 respiratory viruses. At least one virus was detected in 69.6% and dual\/triple viral infections in 12.9%\/1.9% of the patients. Influenza A and B viruses combined were the most frequently detected pathogens, followed by human adenovirus and respiratory syncytial virus (RSV). The other viruses were detected in less than 10% of the patients. Phylogenetic analyses on a representative set of RSV strains revealed that, while otherwise very rare, the RSV\u2010B CB1\/THB genotype cocirculated with other common genotypes. A single wave of influenza virus and RSV activity was observed during the rainy season, providing further support to influenza vaccination before the onset of the rains. This study provides recommendations for influenza vaccination that still needs optimization and highlights the need for revised guidelines for treatment and prevention of respiratory infections in Lao PDR, as well as for increased surveillance efforts.<\/jats:p>","DOI":"10.1002\/jmv.25237","type":"journal-article","created":{"date-parts":[[2018,6,13]],"date-time":"2018-06-13T07:41:34Z","timestamp":1528875694000},"page":"1553-1558","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Etiology of viral respiratory infections in Northern Lao People's Democratic Republic"],"prefix":"10.1002","volume":"90","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0000-1850","authenticated-orcid":false,"given":"Chantal J.","family":"Snoeck","sequence":"first","affiliation":[{"name":"Infectious Disease Research Unit, Department of Infection and Immunity Luxembourg Institute of Health  Esch\u2010sur\u2010Alzette Luxembourg"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valy","family":"Ponghsavath","sequence":"additional","affiliation":[{"name":"Luang Prabang Provincial Hospital Luang Prabang Lao PDR"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nina","family":"Luetteke","sequence":"additional","affiliation":[{"name":"Infectious Disease Research Unit, Department of Infection and Immunity Luxembourg Institute of Health  Esch\u2010sur\u2010Alzette Luxembourg"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabine","family":"Kaufmann","sequence":"additional","affiliation":[{"name":"Laboratoires R\u00e9unis Junglinster Luxembourg"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aur\u00e9lie","family":"Sausy","sequence":"additional","affiliation":[{"name":"Infectious Disease Research Unit, Department of Infection and Immunity Luxembourg Institute of Health  Esch\u2010sur\u2010Alzette Luxembourg"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bounthome","family":"Samountry","sequence":"additional","affiliation":[{"name":"Department of Pathology Faculty of Medicine, University of Health Sciences Vientiane Lao PDR"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prapan","family":"Jutavijittum","sequence":"additional","affiliation":[{"name":"Department of Pathology Faculty of Medicine, Chiang Mai University  Chiang Mai Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernard","family":"Weber","sequence":"additional","affiliation":[{"name":"Laboratoires R\u00e9unis Junglinster Luxembourg"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claude P.","family":"Muller","sequence":"additional","affiliation":[{"name":"Infectious Disease Research Unit, Department of Infection and Immunity Luxembourg Institute of Health  Esch\u2010sur\u2010Alzette Luxembourg"},{"name":"Lao\u2010Lux\u2010Laboratory, Institut Pasteur du Laos  Vientiane Lao PDR"},{"name":"Laboratoire National de Sant\u00e9  Dudelange Luxembourg"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,7,13]]},"reference":[{"key":"e_1_2_8_1_2_1","unstructured":"World Health Organization.WHO Country Cooperation Strategy for the Lao People's Democratic Republic 2012\u20102015.2011: 46.http:\/\/www.wpro.who.int\/laos\/publications\/country_cooperation_lao_2012\u20102015\/en\/. 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