{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T05:11:28Z","timestamp":1782191488970,"version":"3.54.5"},"reference-count":33,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2018,7,13]],"date-time":"2018-07-13T00:00:00Z","timestamp":1531440000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2018,11]]},"abstract":"<jats:p>Blood transfusion services are a vital and integral part of modern healthcare services. However, the risk of transfusion transmittable infections (TTI) has been a major handicap. Therefore, this study was aimed at determining the prevalence of hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV) among blood donors. A retrospective study was conducted to collect data about the blood donors who consecutively donated blood from October 2011 to 2014. A three\u2010year retrospective study was conducted in Mekelle Blood Bank. A data abstraction format was used to collect the sociodemographic and clinical data, and the prevalence of HBV, HCV, and HIV was determined. Data were analyzed using STATA version 10 analytical software. <jats:italic>P<\/jats:italic> value less than 0.05 was considered significant in all the analyses. A total of 10\u2009728 blood donors, median (interquartile range) of age 30 (23\u201045) years and 3750 (34.9%) males were enrolled in this study. Of the participants 407(3.79%), 143(1.33%), and 111(1.03%) blood donors were positive for HBV, HCV, and HIV, respectively. HBV\u2010HIV coinfections were found 10 (1.93%) blood donors, followed by HBV\u2010HCV and HIV\u2010HCV. A significant association between sex and marital status with HBV and HIV infection was found. However, significant association of HCV was observed among sex (\n<jats:italic>X<\/jats:italic>\n<jats:sup>2<\/jats:sup>\u2009=\u200933.18, \n<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001) and occupational (\n<jats:italic>X<\/jats:italic>\n<jats:sup>2<\/jats:sup>\u2009=\u200984.33, \n<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). A significant percentage of HBV, HCV, and HIV among blood donors was observed. To select a donor and collect safe blood risk factors exposing blood donor should be studied, and community\u2010based prevalence studies on\u00a0TTI are also required.<\/jats:p>","DOI":"10.1002\/jmv.25248","type":"journal-article","created":{"date-parts":[[2018,6,15]],"date-time":"2018-06-15T12:47:23Z","timestamp":1529066843000},"page":"1724-1729","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Prevalence of hepatitis B virus, hepatitis C virus, and human immunodeficiency virus among blood donors of Mekelle blood bank, Northern Ethiopia: A three\u2010year retrospective study"],"prefix":"10.1002","volume":"90","author":[{"given":"Berhanu","family":"Degefa","sequence":"first","affiliation":[{"name":"Laboratory Division, Ayder Comprehensive Specialized Hospital, Mekelle University Mekelle Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teklehaymanot","family":"Gebreeyesus","sequence":"additional","affiliation":[{"name":"Laboratory Division, Ayder Comprehensive Specialized Hospital, Mekelle University Mekelle Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zufan","family":"Gebremedhin","sequence":"additional","affiliation":[{"name":"Laboratory Division, Ayder Comprehensive Specialized Hospital, Mekelle University Mekelle Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Getachew","family":"Melkamu","sequence":"additional","affiliation":[{"name":"Medical Microbiology and Immunology Department Mekelle University Mekelle Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsebaha","family":"Gebrekidan","sequence":"additional","affiliation":[{"name":"Medical Microbiology and Immunology Department Mekelle University Mekelle Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haftamu","family":"Hailekiros","sequence":"additional","affiliation":[{"name":"Medical Microbiology and Immunology Department Mekelle University Mekelle Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ephrem","family":"Tsegay","sequence":"additional","affiliation":[{"name":"Medical Microbiology and Immunology Department Mekelle University Mekelle Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4732-9546","authenticated-orcid":false,"given":"Selam","family":"Niguse","sequence":"additional","affiliation":[{"name":"Medical Microbiology and Immunology Department Mekelle University Mekelle Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahmud","family":"Abdulkader","sequence":"additional","affiliation":[{"name":"Medical Microbiology and Immunology Department Mekelle University Mekelle Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,7,13]]},"reference":[{"key":"e_1_2_11_1_2_1","unstructured":"WHO. 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Accessed November 10 2015."},{"key":"e_1_2_11_1_4_1","first-page":"191","volume-title":"Maxey\u2010Rosenau\u2010Last Public Health and Preventive Medicine: Fifteenth Edition","author":"Wallace RB","year":"2007"},{"key":"e_1_2_11_1_5_1","first-page":"S81","article-title":"Prevention of HIV transmission by blood transfusion in the developing world: achievements and continuing challenges","volume":"12","author":"Lackritz EM","year":"1998","journal-title":"AIDS"},{"key":"e_1_2_11_1_6_1","first-page":"86","article-title":"Update on infectious risks associated with blood products","volume":"59","author":"Traineau R","year":"2009","journal-title":"Rev Prat"},{"key":"e_1_2_11_1_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2009.002402.x"},{"key":"e_1_2_11_1_8_1","unstructured":"WHOIRISBlood safety: a strategy for the African region.2001.http:\/\/apps.who.int\/iris\/handle\/10665\/95734. 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HIV Prevalence level shows a drastic Fall in Ethiopia.http:\/\/www.hapco.gov.et\/index.php\/media\u2010room\/news\/item\/12\u2010hiv\u2010prevalence\u2010level\u2010shows\u2010a\u2010drastic\u2010fall\u2010in\u2010ethiopia. 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