{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T21:47:57Z","timestamp":1771019277568,"version":"3.50.1"},"reference-count":60,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2019,2,7]],"date-time":"2019-02-07T00:00:00Z","timestamp":1549497600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["JP17fm0108013"],"award-info":[{"award-number":["JP17fm0108013"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A prospective matched case\u2010control study was conducted to evaluate associations between dietary histories, including consumption of bivalves, diarrhea, and norovirus positive diarrhea in adult ambulatory patients at an outpatient clinic of a hospital in Tokyo, Japan. Ambulatory cases with diarrhea were matched with nondiarrheal control patients, who visited the same clinic. A standardized questionnaire was used to obtain patients\u2019 information, including histories of food consumption and clinical information. Norovirus infection was confirmed using real\u2010time reverse transcription polymerase chain reaction. A total of 207 patients, including 69 diarrheal cases and 138 nondiarrheal cases were included in the analysis. Among them, 60 (29.0%) participants reported consuming bivalves. Norovirus was detected in 35% (24\/69) of diarrheal cases. Of those, 10 (41.7%) reported consumption of bivalves and of those, 6 (60.0%) consumed raw bivalves. The proportion of those who consumed raw bivalves was significantly higher in norovirus\u2010positive diarrheal cases than in norovirus\u2010negative diarrheal cases (25.0% vs 6.7%; odds ratio [OR], 4.67; 95% confidence interval [CI], 1.1\u201020.7) and matched nondiarrheal controls (25.0% vs 6.3%, OR: 5.00; 95% CI, 1.1\u201022.2). The attributable fraction of consuming raw bivalves for norovirus\u2010associated diarrhea to matched nondiarrheal controls was 20.0%. Consuming raw bivalves was substantially attributed to norovirus\u2010associated diarrhea in adult ambulatory patients and preventive measures for reducing the risk associated with consumption of raw bivalves could decrease the incidence of norovirus\u2010associated diarrhea.<\/jats:p>","DOI":"10.1002\/jmv.25416","type":"journal-article","created":{"date-parts":[[2019,1,30]],"date-time":"2019-01-30T16:46:07Z","timestamp":1548866767000},"page":"986-996","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["The association between consuming bivalves, and acute gastroenteritis and norovirus in Tokyo, Japan"],"prefix":"10.1002","volume":"91","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3641-2088","authenticated-orcid":false,"given":"Daiki","family":"Kobayashi","sequence":"first","affiliation":[{"name":"Department of Virology Tohoku University Graduate School of Medicine Sendai Japan"},{"name":"Division of General Internal Medicine, Department of Medicine St. Luke's International Hospital  Tokyo Japan"},{"name":"Division of General Internal Medicine Fujita Health University  Toyoake Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mayuko","family":"Saito","sequence":"additional","affiliation":[{"name":"Department of Virology Tohoku University Graduate School of Medicine Sendai Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuji","family":"Heike","sequence":"additional","affiliation":[{"name":"Division of Joint Research and Development St. Luke's International Hospital  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyoko","family":"Yokota","sequence":"additional","affiliation":[{"name":"Division of General Internal Medicine, Department of Medicine Kagawa University  Kagawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroko","family":"Arioka","sequence":"additional","affiliation":[{"name":"Division of General Internal Medicine, Department of Medicine St. Luke's International Hospital  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hitoshi","family":"Oshitani","sequence":"additional","affiliation":[{"name":"Department of Virology Tohoku University Graduate School of Medicine Sendai Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,2,7]]},"reference":[{"key":"e_1_2_8_1_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra0804575"},{"key":"e_1_2_8_1_3_1","unstructured":"Centers for Disease Control and Prevention.Norovirus Worldwide.2017;https:\/\/www.cdc.gov\/norovirus\/worldwide.html. Accessed July 8 2017."},{"key":"e_1_2_8_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(14)70767-4"},{"key":"e_1_2_8_1_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.coviro.2011.11.005"},{"key":"e_1_2_8_1_6_1","doi-asserted-by":"publisher","DOI":"10.1089\/fpd.2017.2388"},{"key":"e_1_2_8_1_7_1","doi-asserted-by":"publisher","DOI":"10.5365\/wpsar.2017.8.1.008"},{"key":"e_1_2_8_1_8_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid1908.130465"},{"key":"e_1_2_8_1_9_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid1604.090723"},{"key":"e_1_2_8_1_10_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1001923"},{"key":"e_1_2_8_1_11_1","unstructured":"Japanese Ministry of Health Labour and Welfare.Summary document of food poisning.2017;http:\/\/www.mhlw.go.jp\/stf\/seisakunitsuite\/bunya\/kenkou_iryou\/shokuhin\/syokuchu\/04.html. Accessed 8 July 2017."},{"key":"e_1_2_8_1_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2016.03.016"},{"key":"e_1_2_8_1_13_1","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.01046-12"},{"key":"e_1_2_8_1_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jviromet.2008.07.022"},{"key":"e_1_2_8_1_15_1","doi-asserted-by":"publisher","DOI":"10.4315\/0362-028X-71.7.1427"},{"key":"e_1_2_8_1_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijfoodmicro.2013.06.023"},{"key":"e_1_2_8_1_17_1","doi-asserted-by":"publisher","DOI":"10.4315\/0362-028X.JFP-16-083"},{"key":"e_1_2_8_1_18_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00305-08"},{"key":"e_1_2_8_1_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.marenvres.2017.08.009"},{"key":"e_1_2_8_1_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijfoodmicro.2016.10.028"},{"key":"e_1_2_8_1_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12560-016-9244-6"},{"key":"e_1_2_8_1_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2015.10.004"},{"key":"e_1_2_8_1_23_1","doi-asserted-by":"publisher","DOI":"10.4315\/0362-028X.JFP-13-430"},{"key":"e_1_2_8_1_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-1605(00)00248-8"},{"key":"e_1_2_8_1_25_1","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.66.8.3241-3248.2000"},{"key":"e_1_2_8_1_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0166-0934(00)00174-9"},{"key":"e_1_2_8_1_27_1","doi-asserted-by":"publisher","DOI":"10.4315\/0362-028X-70.9.2140"},{"key":"e_1_2_8_1_28_1","doi-asserted-by":"publisher","DOI":"10.1086\/339883"},{"key":"e_1_2_8_1_29_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm860"},{"key":"e_1_2_8_1_30_1","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.04096-15"},{"key":"e_1_2_8_1_31_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid0912.020076"},{"key":"e_1_2_8_1_32_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268810002839"},{"key":"e_1_2_8_1_33_1","unstructured":"Tokyo Metropolitan Infectious Disease Surveillance Center.Epidemic situation of infectious gastroenteritis.2017;http:\/\/idsc.tokyo\u2010eiken.go.jp\/en\/. Accessed 25 February 2017."},{"key":"e_1_2_8_1_34_1","unstructured":"World Health Organization.Diarrhoeal disease.2013;http:\/\/www.who.int\/mediacentre\/factsheets\/fs330\/en\/. Accessed 25 February 2017."},{"key":"e_1_2_8_1_35_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cix423"},{"key":"e_1_2_8_1_36_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268814003288"},{"key":"e_1_2_8_1_37_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268810000439"},{"key":"e_1_2_8_1_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2008.10.009"},{"key":"e_1_2_8_1_39_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.brs.0000164099.92112.29"},{"key":"e_1_2_8_1_40_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2009.06015.x"},{"key":"e_1_2_8_1_41_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.41.4.1548-1557.2003"},{"key":"e_1_2_8_1_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0166-0934(01)00404-9"},{"key":"e_1_2_8_1_43_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.42.10.4679-4685.2004"},{"key":"e_1_2_8_1_44_1","unstructured":"XuHang LiuXiaofang TohmaKentaroet al. A novel sensitive protocol for genotyping of norovirus genogroup II recombinants [press release]. Paper presented at the 70th Annual Meeting of Tohoku Society of Microbiology2016."},{"key":"e_1_2_8_1_45_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cis788"},{"key":"e_1_2_8_1_46_1","doi-asserted-by":"publisher","DOI":"10.1186\/1751-0473-3-17"},{"key":"e_1_2_8_1_47_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a115101"},{"key":"e_1_2_8_1_48_1","unstructured":"Japanese Ministry of Health Labour and Welfare.Statistical data of food poisoning.2018;http:\/\/www.mhlw.go.jp\/stf\/seisakunitsuite\/bunya\/kenkou_iryou\/shokuhin\/syokuchu\/04.html. Accessed 6 March 2018."},{"key":"e_1_2_8_1_49_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciw072"},{"key":"e_1_2_8_1_50_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-016-1702-0"},{"key":"e_1_2_8_1_51_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.ss6412a1"},{"key":"e_1_2_8_1_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2014.06.022"},{"key":"e_1_2_8_1_53_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268811002305"},{"key":"e_1_2_8_1_54_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jis206"},{"key":"e_1_2_8_1_55_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwt287"},{"key":"e_1_2_8_1_56_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa044307"},{"key":"e_1_2_8_1_57_1","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.72.12.1329"},{"key":"e_1_2_8_1_58_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jis206"},{"key":"e_1_2_8_1_59_1","doi-asserted-by":"publisher","DOI":"10.1086\/421948"},{"key":"e_1_2_8_1_60_1","doi-asserted-by":"publisher","DOI":"10.3390\/v2030748"},{"key":"e_1_2_8_1_61_1","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofw026"}],"container-title":["Journal of Medical Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjmv.25416","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmv.25416","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jmv.25416","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jmv.25416","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,10]],"date-time":"2023-09-10T09:13:59Z","timestamp":1694337239000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jmv.25416"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2,7]]},"references-count":60,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2019,6]]}},"alternative-id":["10.1002\/jmv.25416"],"URL":"https:\/\/doi.org\/10.1002\/jmv.25416","archive":["Portico"],"relation":{},"ISSN":["0146-6615","1096-9071"],"issn-type":[{"value":"0146-6615","type":"print"},{"value":"1096-9071","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,2,7]]},"assertion":[{"value":"2018-08-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-12-04","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-02-07","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}