{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T20:44:21Z","timestamp":1785444261268,"version":"3.56.0"},"reference-count":38,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2019,11,18]],"date-time":"2019-11-18T00:00:00Z","timestamp":1574035200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Virology"],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Men who have sex with men (MSM) continue to be disproportionately impacted by human immunodeficiency virus (HIV) and syphilis in China. Little is known about HIV and syphilis infections among MSM in Xi'an, a developing city in Northwest China.\u00a0A cross\u2010sectional study with recruitment via snowball sampling was conducted to collect HIV and syphilis infection status and risk factors among MSM in Xi'an between April 2013 to December 2016.\u00a0Among the 5000 participants, the mean age was 29.0 years (SD 7.7) and the prevalence of HIV, syphilis, and coinfection was 6.5%, 2.2%, and 0.4%, respectively. There was no significant change in HIV prevalence from 2013 to 2016, while the prevalence of syphilis and coinfection showed a downward trend. Multiple logistic regression analyses found that being over 25 years old (OR\u2009=\u20091.647), junior high school\/middle school education and below (OR\u2009=\u20093.085), with a sexual role of passive or versatile (OR\u2009=\u20093.300; OR\u2009=\u20092.337), rush poppers use during the last 6 months (OR\u2009=\u20091.660) and syphilis infection (OR\u2009=\u20092.235) were more likely to acquire HIV infection, whereas used condoms in the last episode of anal sex (OR\u2009=\u20090.572) and tested HIV antibody previously (OR\u2009=\u20090.252) were protective factors for HIV infection.\u00a0HIV prevalence among MSM in Xi'an was stable, whereas the prevalence of syphilis and coinfection showed a downward trend. Interventions to promote HIV and sexually transmitted disease testing and condom use should be strengthened, especially for MSM with low education.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jmv.25622","type":"journal-article","created":{"date-parts":[[2019,11,7]],"date-time":"2019-11-07T12:28:24Z","timestamp":1573129704000},"page":"1141-1147","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Prevalence and protective factors of HIV and syphilis infection among men who have sex with men in Northwest China"],"prefix":"10.1002","volume":"92","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9092-6282","authenticated-orcid":false,"given":"Lirong","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Epidemiology and Biostatistics, School of Public Health Xi'an Jiaotong University Health Science Center  Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony 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